Feline morbillivirus in Northern Italy: prevalence in urine and kidneys with and without renal disease.
Chronic kidney disease
Clinical pathology
Feline morbillivirus
Urinalysis
Journal
Veterinary microbiology
ISSN: 1873-2542
Titre abrégé: Vet Microbiol
Pays: Netherlands
ID NLM: 7705469
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
06
09
2018
revised:
23
04
2019
accepted:
23
04
2019
entrez:
10
6
2019
pubmed:
10
6
2019
medline:
27
6
2019
Statut:
ppublish
Résumé
Feline morbillivirus (FeMV) is an emerging virus that was first described in Hong Kong in 2012. Several reports suggested the epidemiological association of FeMV infection with chronic kidney disease (CKD) in cats. The aim of this study was to investigate the presence and the genetic diversity of FeMV as well as the relationship between FeMV infection and CKD in cats from Northern Italy. Urine (n = 81) and kidney samples (n = 27) from 92 cats admitted to the Veterinary Teaching Hospital of the University of Milan between 2014 and 2017 were investigated for FeMV infection. FeMV RNA was detected in one urine sample (1.23%; 95% CI: 0.03-6.68%) and in two kidneys (7.40%; 95% CI: 0.91-24.28%). FeMV RNA was revealed only in urine or kidneys of cats without evidence of CKD. Phylogenetic analysis showed that the three strains clustered with FeMV strains retrieved from public database, forming a distinct sub-cluster of FeMV. The presence of distinct genotypes of FeMV found in this study is in accordance with previous studies demonstrating that FeMV strains are genetically diverse. A clear relationship between the presence of FeMV infection and CKD in the cats from Northern Italy was not observed, confirming recent reports that do not support the hypothesis that FeMV infection is associated with the development of CKD.
Identifiants
pubmed: 31176399
pii: S0378-1135(18)31049-6
doi: 10.1016/j.vetmic.2019.04.027
pmc: PMC7127068
pii:
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
133-139Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
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