Endocarditis Caused by Highly Penicillin-Resistant Viridans Group Streptococci: Still Room for Vancomycin-Based Regimens.

Adult Drug Resistance, Bacterial / drug effects Endocarditis, Bacterial / drug therapy Humans Male Middle Aged Penicillins / therapeutic use Vancomycin / therapeutic use Viridans Streptococci / drug effects
animal models combination therapy high-level penicillin resistance in vitro infective endocarditis viridans group streptococci

Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
08 2019
Historique:
received: 08 03 2019
accepted: 04 06 2019
pubmed: 12 6 2019
medline: 21 5 2020
entrez: 12 6 2019
Statut: epublish

Résumé

Optimal treatment options remain unknown for infective endocarditis (IE) caused by penicillin-resistant (PEN-R) viridans group streptococcal (VGS) strains. The aims of this study were to report two cases of highly PEN-R VGS IE, perform a literature review, and evaluate various antibiotic combinations

Identifiants

DOI: 10.1128/AAC.00516-19 PMID: 31182540 PMC: PMC6658762
pubmed: 31182540
pii: AAC.00516-19
doi: 10.1128/AAC.00516-19
pmc: PMC6658762
pii:
doi:

Substances chimiques

Penicillins 0
Vancomycin 6Q205EH1VU

Types de publication

Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI130056
Pays : United States

Investigateurs

Jose M Miró (JM)
Juan Ambrosioni (J)
Juan M Pericàs (JM)
Adrian Téllez (A)
Marta Hernandez-Meneses (M)
Delia Garcia-Pares (D)
Asunción Moreno (A)
Cristina Garcia de la Maria (CG)
Javier Garcia-González (J)
Manel Almela (M)
Climent Casals (C)
Francesc Marco (F)
Jordi Vila (J)
Eduard Quintana (E)
Elena Sandoval (E)
Juan C Paré (JC)
Carlos Falces (C)
Daniel Pereda (D)
Ramon Cartañá (R)
Salvador Ninot (S)
Manel Azqueta (M)
Marta Sitges (M)
Barbara Vidal (B)
José L Pomar (JL)
Manuel Castella (M)
José M Tolosana (JM)
José Ortiz (J)
Guillermina Fita (G)
Irene Rovira (I)
David Fuster (D)
Jose Ramírez (J)
Mercè Brunet (M)
Dolors Soy (D)
Pedro Castro (P)
Jaume Llopis (J)

Informations de copyright

Copyright © 2019 American Society for Microbiology.

Références

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Auteurs

Juan M Pericàs (JM)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Clinical Direction on Infectious Diseases and Clinical Microbiology, Hospital Universitari Arnau de Vilanova, IRB Lleida, Spain.

Ruvandhi Nathavitharana (R)

Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
ORCID: 0000-0002-3544-5021

Cristina Garcia-de-la-Mària (C)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Carles Falces (C)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Juan Ambrosioni (J)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Manel Almela (M)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Javier García-González (J)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Eduard Quintana (E)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Francesc Marco (F)

Hospital Clinic of Barcelona, ISGlobal, University of Barcelona, Barcelona, Spain.

Asunción Moreno (A)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Arnold S Bayer (AS)

LA Biomedical Research Institute, Torrance, California, USA.
Geffen School of Medicine at UCLA, Los Angeles, California, USA.

José M Miró (JM)

Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain jmmiro@ub.edu.

Adolf W Karchmer (AW)

Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Endocarditis Caused by Highly...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › Résistance bactérienne aux médicaments › Endocarditis Caused by Highly...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Endocardite › Endocardite bactérienne › Endocarditis Caused by Highly...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Endocarditis Caused by Highly...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Endocarditis Caused by Highly...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Pénicillines › Endocarditis Caused by Highly...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Glycopeptides › Vancomycine › Endocarditis Caused by Highly...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Lactobacillales › Streptococcaceae › Streptococcus › Streptocoques viridans › Endocarditis Caused by Highly...