Single isocenter stereotactic radiosurgery for patients with multiple brain metastases: dosimetric comparison of VMAT and a dedicated DCAT planning tool.
Aged
Algorithms
Brain Neoplasms
/ secondary
Female
Humans
Male
Middle Aged
Neoplasms
/ pathology
Organs at Risk
/ radiation effects
Prognosis
Radiosurgery
/ methods
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
/ methods
Radiotherapy, Conformal
/ methods
Radiotherapy, Intensity-Modulated
/ methods
Retrospective Studies
Brain metastases
Dynamic conformal arc therapy
Single Isocenter
Stereotactic radiosurgery
VMAT
Journal
Radiation oncology (London, England)
ISSN: 1748-717X
Titre abrégé: Radiat Oncol
Pays: England
ID NLM: 101265111
Informations de publication
Date de publication:
11 Jun 2019
11 Jun 2019
Historique:
received:
12
02
2019
accepted:
31
05
2019
entrez:
13
6
2019
pubmed:
13
6
2019
medline:
18
12
2019
Statut:
epublish
Résumé
In this dosimetric study, a dedicated planning tool for single isocenter stereotactic radiosurgery for multiple brain metastases using dynamic conformal arc therapy (DCAT) was compared to standard volumetric modulated arc therapy (VMAT). Twenty patients with a total of 66 lesions who were treated with the DCAT tool were included in this study. Single fraction doses of 15-20 Gy were prescribed to each lesion. Patients were re-planned using non-coplanar VMAT. Number of monitor units as well as V The automated DCAT planning tool performed significantly better in terms of all investigated metrics (p < 0.05), in particular healthy brain sparing (V The dedicated DCAT planning tool performed better than VMAT in terms of healthy brain sparing and treatment efficiency, in particular for nearly spherical lesions. In contrast, VMAT can be superior in cases with irregularly shaped lesions.
Sections du résumé
BACKGROUND
BACKGROUND
In this dosimetric study, a dedicated planning tool for single isocenter stereotactic radiosurgery for multiple brain metastases using dynamic conformal arc therapy (DCAT) was compared to standard volumetric modulated arc therapy (VMAT).
METHODS
METHODS
Twenty patients with a total of 66 lesions who were treated with the DCAT tool were included in this study. Single fraction doses of 15-20 Gy were prescribed to each lesion. Patients were re-planned using non-coplanar VMAT. Number of monitor units as well as V
RESULTS
RESULTS
The automated DCAT planning tool performed significantly better in terms of all investigated metrics (p < 0.05), in particular healthy brain sparing (V
CONCLUSIONS
CONCLUSIONS
The dedicated DCAT planning tool performed better than VMAT in terms of healthy brain sparing and treatment efficiency, in particular for nearly spherical lesions. In contrast, VMAT can be superior in cases with irregularly shaped lesions.
Identifiants
pubmed: 31186023
doi: 10.1186/s13014-019-1315-z
pii: 10.1186/s13014-019-1315-z
pmc: PMC6560766
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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