Incidence of Ductal Carcinoma


Journal

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
ISSN: 1538-7755
Titre abrégé: Cancer Epidemiol Biomarkers Prev
Pays: United States
ID NLM: 9200608

Informations de publication

Date de publication:
08 2019
Historique:
received: 21 11 2018
revised: 01 03 2019
accepted: 03 06 2019
pubmed: 13 6 2019
medline: 18 9 2020
entrez: 13 6 2019
Statut: ppublish

Résumé

In absence of definitive molecular risk markers, clinical management of patients diagnosed with ductal carcinoma The Surveillance, Epidemiology, and End Results registry was queried for patients diagnosed with DCIS from 2000 to 2014 (18 registries). Joinpoint regression analyses were used to compute age- and race-stratified trends in age-adjusted incidence of DCIS. The patterns of DCIS incidence were compared against mammography utilization data from the National Health Interview Survey. Between 2000 and 2014, overall DCIS incidence in the U.S. population was stable ( Overall DCIS incidence rates have remained stable between 2000 and 2014. However, subgroup analyses revealed an increase in incidence among both younger women and black women. DCIS incidence trends did not correlate with the mammography uptake patterns, suggesting that etiologic factors other than screening may be leading to an increased DCIS incidence in these groups.

Sections du résumé

BACKGROUND
In absence of definitive molecular risk markers, clinical management of patients diagnosed with ductal carcinoma
METHODS
The Surveillance, Epidemiology, and End Results registry was queried for patients diagnosed with DCIS from 2000 to 2014 (18 registries). Joinpoint regression analyses were used to compute age- and race-stratified trends in age-adjusted incidence of DCIS. The patterns of DCIS incidence were compared against mammography utilization data from the National Health Interview Survey.
RESULTS
Between 2000 and 2014, overall DCIS incidence in the U.S. population was stable (
CONCLUSIONS
Overall DCIS incidence rates have remained stable between 2000 and 2014. However, subgroup analyses revealed an increase in incidence among both younger women and black women.
IMPACT
DCIS incidence trends did not correlate with the mammography uptake patterns, suggesting that etiologic factors other than screening may be leading to an increased DCIS incidence in these groups.

Identifiants

pubmed: 31186262
pii: 1055-9965.EPI-18-1262
doi: 10.1158/1055-9965.EPI-18-1262
pmc: PMC6679771
mid: NIHMS1531560
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1316-1323

Subventions

Organisme : NCI NIH HHS
ID : K99 CA207872
Pays : United States
Organisme : NCI NIH HHS
ID : R00 CA207872
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA185138
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA222508
Pays : United States

Informations de copyright

©2019 American Association for Cancer Research.

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Auteurs

Marc D Ryser (MD)

Department of Population Health Sciences, Duke University Medical Center, Durham, North Carolina. marc.ryser@duke.edu.
Department of Mathematics, Duke University, Durham, North Carolina.

Laura H Hendrix (LH)

Department of Biostatistics & Bioinformatics, Duke University Medical Center, Durham, North Carolina.

Mathias Worni (M)

Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Yiling Liu (Y)

Duke Center for Applied Genomics & Precision Medicine, Duke University Medical Center, Durham, North Carolina.

Terry Hyslop (T)

Department of Biostatistics & Bioinformatics, Duke University Medical Center, Durham, North Carolina.

E Shelley Hwang (ES)

Department of Surgery, Division of Advanced Oncologic and GI Surgery, Duke University Medical Center, Durham, North Carolina.

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Classifications MeSH