Left Atrial Volume Index Is Associated With Cardioembolic Stroke and Atrial Fibrillation Detection After Embolic Stroke of Undetermined Source.


Journal

Stroke
ISSN: 1524-4628
Titre abrégé: Stroke
Pays: United States
ID NLM: 0235266

Informations de publication

Date de publication:
08 2019
Historique:
pubmed: 14 6 2019
medline: 7 3 2020
entrez: 14 6 2019
Statut: ppublish

Résumé

Background and Purpose- Left atrial enlargement has been shown to be associated with ischemic stroke, but the association with embolic stroke mechanisms remains unknown. We aim to study the associations between left atrial volume index (LAVI) and embolic stroke subtypes and atrial fibrillation (AF) detection on cardiac event monitoring in patients with embolic stroke of unknown source. Methods- Data were collected from a prospective cohort of consecutive patients with ischemic stroke admitted to a comprehensive stroke center over 18 months. Stroke subtype was classified into cardioembolic stroke, noncardioembolic stroke of determined mechanism (NCE), or embolic stroke of undetermined source (ESUS). Univariate and prespecified multivariable analyses were performed to assess associations between LAVI and stroke subtype and AF detection in patients with ESUS. Results- Of 1224 consecutive patients identified during the study period, 1020 (82.6%) underwent transthoracic echocardiography and had LAVI measurements. LAVI was greater in patients with cardioembolic stroke than NCE (41.4 mL/m

Identifiants

pubmed: 31189435
doi: 10.1161/STROKEAHA.119.025384
pmc: PMC6646078
mid: NIHMS1530247
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1997-2001

Subventions

Organisme : American Heart Association-American Stroke Association
ID : 17MCPRP33670965
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn

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Auteurs

Kevin Jordan (K)

From the Division of Cardiology, Department of Internal Medicine (K.J., A.P., C.S.), the Warren Alpert Medical School of Brown University, Providence, RI.

Shadi Yaghi (S)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.
Department of Neurology, New York University Langone Health (S.Y.).

Athena Poppas (A)

From the Division of Cardiology, Department of Internal Medicine (K.J., A.P., C.S.), the Warren Alpert Medical School of Brown University, Providence, RI.

Andrew D Chang (AD)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.

Brian Mac Grory (B)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.

Shawna Cutting (S)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.

Tina Burton (T)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.

Mahesh Jayaraman (M)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.
Department of Diagnostic Imaging (M.J.), the Warren Alpert Medical School of Brown University, Providence, RI.
Department of Neurosurgery (M.J.), the Warren Alpert Medical School of Brown University, Providence, RI.

Georgios Tsivgoulis (G)

Departments of Neurology, University of Tennessee, Memphis (G.T.).
Department of Neurology, National and Kapodistrian University of Athens, Greece (G.T.).

M Khaled Sabeh (MK)

Division of Cardiology, Department of Internal Medicine, Harvard Medical School, Boston, MA (M.K.S.).

Alexander E Merkler (AE)

Departments of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, NY (A.M., H.K.).

Hooman Kamel (H)

Departments of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, NY (A.M., H.K.).

Mitchell S V Elkind (MSV)

Department of Neurology, Vagelos College of Physicians and Surgeons (M.S.V.E.), Columbia University, NY.
Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, NY.

Karen Furie (K)

Department of Neurology (S.Y., A.D.C., B.M.G., S.C., T.B., M.J., K.F.), the Warren Alpert Medical School of Brown University, Providence, RI.

Christopher Song (C)

From the Division of Cardiology, Department of Internal Medicine (K.J., A.P., C.S.), the Warren Alpert Medical School of Brown University, Providence, RI.

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