The impact of skin care products on skin chemistry and microbiome dynamics.
16S rRNA sequencing
Bacteria
Mass spectrometry
Metabolomics
Skin
Skin care products
Journal
BMC biology
ISSN: 1741-7007
Titre abrégé: BMC Biol
Pays: England
ID NLM: 101190720
Informations de publication
Date de publication:
12 06 2019
12 06 2019
Historique:
received:
20
02
2019
accepted:
30
04
2019
entrez:
14
6
2019
pubmed:
14
6
2019
medline:
9
11
2019
Statut:
epublish
Résumé
Use of skin personal care products on a regular basis is nearly ubiquitous, but their effects on molecular and microbial diversity of the skin are unknown. We evaluated the impact of four beauty products (a facial lotion, a moisturizer, a foot powder, and a deodorant) on 11 volunteers over 9 weeks. Mass spectrometry and 16S rRNA inventories of the skin revealed decreases in chemical as well as in bacterial and archaeal diversity on halting deodorant use. Specific compounds from beauty products used before the study remain detectable with half-lives of 0.5-1.9 weeks. The deodorant and foot powder increased molecular, bacterial, and archaeal diversity, while arm and face lotions had little effect on bacterial and archaeal but increased chemical diversity. Personal care product effects last for weeks and produce highly individualized responses, including alterations in steroid and pheromone levels and in bacterial and archaeal ecosystem structure and dynamics. These findings may lead to next-generation precision beauty products and therapies for skin disorders.
Sections du résumé
BACKGROUND
Use of skin personal care products on a regular basis is nearly ubiquitous, but their effects on molecular and microbial diversity of the skin are unknown. We evaluated the impact of four beauty products (a facial lotion, a moisturizer, a foot powder, and a deodorant) on 11 volunteers over 9 weeks.
RESULTS
Mass spectrometry and 16S rRNA inventories of the skin revealed decreases in chemical as well as in bacterial and archaeal diversity on halting deodorant use. Specific compounds from beauty products used before the study remain detectable with half-lives of 0.5-1.9 weeks. The deodorant and foot powder increased molecular, bacterial, and archaeal diversity, while arm and face lotions had little effect on bacterial and archaeal but increased chemical diversity. Personal care product effects last for weeks and produce highly individualized responses, including alterations in steroid and pheromone levels and in bacterial and archaeal ecosystem structure and dynamics.
CONCLUSIONS
These findings may lead to next-generation precision beauty products and therapies for skin disorders.
Identifiants
pubmed: 31189482
doi: 10.1186/s12915-019-0660-6
pii: 10.1186/s12915-019-0660-6
pmc: PMC6560912
doi:
Substances chimiques
Cosmetics
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
47Subventions
Organisme : NIAMS NIH HHS
ID : R21 AR071731
Pays : United States
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