Limiting factors for autologous transplantation among transplant-eligible multiple myeloma patients: Lesson from a Tertiary Cancer Centre in rural India.
Autologous transplantation
Malabar Cancer Centre
Myeloma patients
WHO SORT-IT
Journal
Leukemia research
ISSN: 1873-5835
Titre abrégé: Leuk Res
Pays: England
ID NLM: 7706787
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
received:
05
05
2019
revised:
05
06
2019
accepted:
06
06
2019
pubmed:
15
6
2019
medline:
21
5
2020
entrez:
15
6
2019
Statut:
ppublish
Résumé
There is limited data from low and middle income countries on the exact proportion of Myeloma patients undergoing transplant even if they are eligible for the same. In this retrospective analysis of all newly diagnosed transplant eligible Myeloma treated between January 2011 to June 2017, number of patients undergoing transplant were recorded and among those not opting for transplant, reasons for the same were noted. Among 89 eligible patients, 23 (26%) patients could undergo transplantation. Most common reasons for not undergoing transplant were fear of the complications in 42 (47%) and financial reasons in 41 (46%) of patients. The transplanted group had better progression free survival when compared against the non-transplanted group (3 year PFS of 80% versus 36%, HR = 0.09, 95%CI 0.02-0.4, p = 0.001). Future studies may be conducted to arrive at measures, for correcting the transplant related concerns and fears, through psycho-social interventions.
Identifiants
pubmed: 31200146
pii: S0145-2126(19)30113-4
doi: 10.1016/j.leukres.2019.106167
pii:
doi:
Types de publication
Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106167Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.