Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial.
Arthralgia
/ diagnosis
Australia
Comorbidity
Exercise Therapy
/ methods
Female
Humans
Knee Joint
/ physiopathology
Male
Middle Aged
Muscle Strength
/ physiology
Obesity
/ epidemiology
Osteoarthritis, Knee
/ complications
Pain Measurement
Physical Functional Performance
Quadriceps Muscle
/ physiopathology
Quality of Life
Randomized Controlled Trials as Topic
Treatment Outcome
Weight-Bearing
Clinical trial
Exercise
Knee
Obesity
Osteoarthritis
Physiotherapy
RCT
Journal
BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565
Informations de publication
Date de publication:
18 Jun 2019
18 Jun 2019
Historique:
received:
06
11
2018
accepted:
31
05
2019
entrez:
19
6
2019
pubmed:
19
6
2019
medline:
18
12
2019
Statut:
epublish
Résumé
Clinical guidelines recommend exercise as a core treatment for individuals with knee osteoarthritis (OA). However, the best type of exercise for clinical benefits is not clear, particularly in different OA subgroups. Obesity is a common co-morbidity in people with knee OA. There is some evidence suggesting that non-weight bearing exercise may be more effective than weight bearing exercise in patients with medial knee OA and obesity. To compare the efficacy of two different exercise programs (weight bearing functional exercise and non-weight bearing quadriceps strengthening) on pain and physical function for people ≥50 years with painful medial knee OA and obesity (body mass index ≥30 kg/m This study will compare the efficacy of two different 12-week physiotherapist-prescribed, home-based exercise programs for people with medial knee OA and obesity. Findings will provide valuable information to help inform exercise prescription in this common OA patient subgroup. Australian New Zealand Clinical Trials Registry reference: ACTRN12617001013358 , 14/7/2017.
Sections du résumé
BACKGROUND
BACKGROUND
Clinical guidelines recommend exercise as a core treatment for individuals with knee osteoarthritis (OA). However, the best type of exercise for clinical benefits is not clear, particularly in different OA subgroups. Obesity is a common co-morbidity in people with knee OA. There is some evidence suggesting that non-weight bearing exercise may be more effective than weight bearing exercise in patients with medial knee OA and obesity.
METHODS
METHODS
To compare the efficacy of two different exercise programs (weight bearing functional exercise and non-weight bearing quadriceps strengthening) on pain and physical function for people ≥50 years with painful medial knee OA and obesity (body mass index ≥30 kg/m
DISCUSSION
CONCLUSIONS
This study will compare the efficacy of two different 12-week physiotherapist-prescribed, home-based exercise programs for people with medial knee OA and obesity. Findings will provide valuable information to help inform exercise prescription in this common OA patient subgroup.
TRIAL REGISTRATION
BACKGROUND
Australian New Zealand Clinical Trials Registry reference: ACTRN12617001013358 , 14/7/2017.
Identifiants
pubmed: 31208435
doi: 10.1186/s12891-019-2662-5
pii: 10.1186/s12891-019-2662-5
pmc: PMC6580522
doi:
Types de publication
Clinical Trial Protocol
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
291Subventions
Organisme : National Health and Medical Research Council
ID : 1091302
Références
Ann Rheum Dis. 1999 Mar;58(3):151-5
pubmed: 10364912
J Behav Med. 2000 Aug;23(4):351-65
pubmed: 10984864
Curr Rheumatol Rep. 2001 Apr;3(2):101-6
pubmed: 11286664
Arthritis Rheum. 2001 Oct;45(5):453-61
pubmed: 11642645
Pain. 2001 Nov;94(2):149-58
pubmed: 11690728
Arch Phys Med Rehabil. 2002 Nov;83(11):1566-71
pubmed: 12422327
J Clin Epidemiol. 2003 Feb;56(2):138-47
pubmed: 12654408
Arthritis Rheum. 2005 Jul;52(7):2026-32
pubmed: 15986358
Br J Clin Psychol. 2005 Jun;44(Pt 2):227-39
pubmed: 16004657
Pain. 2006 Mar;121(1-2):151-7
pubmed: 16472915
Ann Intern Med. 2008 Feb 19;148(4):295-309
pubmed: 18283207
Arch Phys Med Rehabil. 2008 Jun;89(6):1146-54
pubmed: 18503813
Arthritis Rheum. 2008 Jul 15;59(7):943-51
pubmed: 18576289
Med Clin North Am. 2009 Jan;93(1):145-59, xi-xii
pubmed: 19059026
J Rehabil Med. 2010 Apr;42(4):323-31
pubmed: 20461334
Knee. 2011 Dec;18(6):417-23
pubmed: 20850976
J Pharmacol Pharmacother. 2010 Jul;1(2):100-7
pubmed: 21350618
BMC Musculoskelet Disord. 2011 Dec 05;12:276
pubmed: 22141334
Inflammopharmacology. 2012 Apr;20(2):53-8
pubmed: 22237485
Arthritis Care Res (Hoboken). 2012 Jun;64(6):862-71
pubmed: 22290689
Arthritis Care Res (Hoboken). 2012 Jul;64(7):968-76
pubmed: 22550055
Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S350-70
pubmed: 22588756
Arthritis Care Res (Hoboken). 2013 Jan;65(1):34-43
pubmed: 22674832
Ann Intern Med. 2013 Feb 5;158(3):200-7
pubmed: 23295957
Osteoarthritis Cartilage. 2013 Aug;21(8):1042-52
pubmed: 23680877
Reg Anesth Pain Med. 2013 Nov-Dec;38(6):481-91
pubmed: 24141874
Ann Rheum Dis. 2014 Jun;73(6):982-9
pubmed: 24550172
Ann Rheum Dis. 2014 Jul;73(7):1323-30
pubmed: 24553908
Int J Epidemiol. 2014 Jun;43(3):962-70
pubmed: 24603316
BMJ. 2014 Mar 07;348:g1687
pubmed: 24609605
Arthritis Rheumatol. 2014 Apr;66(4):950-9
pubmed: 24757146
Best Pract Res Clin Rheumatol. 2014 Feb;28(1):5-15
pubmed: 24792942
Arthritis Care Res (Hoboken). 2015 Sep;67(9):1281-8
pubmed: 25623617
J Pain Res. 2015 Feb 09;8:63-77
pubmed: 25709495
Osteoarthritis Cartilage. 2015 May;23(5):787-97
pubmed: 25952349
Osteoarthritis Cartilage. 2015 May;23(5):803-14
pubmed: 25952351
Br J Sports Med. 2015 Dec;49(24):1554-7
pubmed: 26405113
Arthritis Care Res (Hoboken). 2017 Jan;69(1):84-94
pubmed: 27111441
Physiotherapy. 2017 Jun;103(2):180-185
pubmed: 27913064
J Orthop Sports Phys Ther. 2017 Feb;47(2):67-79
pubmed: 28142365
Ann Intern Med. 2017 Apr 4;166(7):453-462
pubmed: 28241215
Arthritis Rheum. 1989 Jan;32(1):37-44
pubmed: 2912463
J Rheumatol. 1988 Dec;15(12):1833-40
pubmed: 3068365
Arthritis Rheum. 1986 Aug;29(8):1039-49
pubmed: 3741515
Eur J Appl Physiol Occup Physiol. 1985;54(4):343-9
pubmed: 4065121
J Clin Epidemiol. 1993 Feb;46(2):153-62
pubmed: 8437031
J Rheumatol. 1996 Feb;23(2):328-31
pubmed: 8882041
J Orthop Sports Phys Ther. 1998 Aug;28(2):88-96
pubmed: 9699158