[Outcome of locally advanced Darier and Ferrand dermatofibrosarcoma: about a case and literature review].

Une réponse complète d'un dermatofibrosarcome de Darrier et Ferrand localement avancé: à propos d'un cas et revue de la littérature.

Journal

The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926

Informations de publication

Date de publication:
2019
Historique:
received: 12 07 2016
accepted: 12 11 2018
entrez: 22 6 2019
pubmed: 22 6 2019
medline: 3 7 2019
Statut: epublish

Résumé

Darier and Ferrand dermatofibrosarcoma (DFS) is a rare skin tumor characterized by its local aggressiveness and a high risk of recurrences. Prognosis depends essentially on the quality of treatment. Complete response in Darier and Ferrand dermatofibrosarcoma with healthy margins, initially judged inoperable after 1 year of neoadjuvant imatinib-based treatment, has been rarely described in literature. We here report the case of a young female patient treated in the Department of Medical Oncology in FES for locally advanced DFS with complete response, in order to assess the role of imatinib and of targeted therapies in the treatment of DFS.

Identifiants

pubmed: 31223387
doi: 10.11604/pamj.2019.32.97.10293
pii: PAMJ-32-97
pmc: PMC6560964
doi:

Substances chimiques

Antineoplastic Agents 0
Imatinib Mesylate 8A1O1M485B

Types de publication

Case Reports Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

97

Déclaration de conflit d'intérêts

Les auteurs ne déclarent aucun conflit d'intérêts.

Références

Cancer Res. 1999 Aug 1;59(15):3719-23
pubmed: 10446987
Int J Cancer. 2001 May 1;92(3):354-60
pubmed: 11291071
J Clin Oncol. 2005 Feb 1;23(4):866-73
pubmed: 15681532
J Cancer Res Clin Oncol. 2009 May;135(5):653-65
pubmed: 19205737
Ann Surg Oncol. 2010 Aug;17(8):2112-8
pubmed: 20354798
Curr Opin Oncol. 2012 Jul;24(4):419-24
pubmed: 22510939
Arch Dermatol. 2012 Sep;148(9):1055-63
pubmed: 22986859
Bull Cancer. 2015 Jan;102(1):6-16
pubmed: 25609490

Auteurs

Hajar Ouahbi (H)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Lamiae Amadour (L)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Fatimazahra Elmernissi (F)

Service de Dermatologie CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Layla Tahiri (L)

Servie d'Anatomopathologie CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Taoufik Harmouch (T)

Servie d'Anatomopathologie CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Zineb Benbrahim (Z)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Fatimazahra Elmrabet (F)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Samia Arifi (S)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Ayat Allah Oufkigh (AA)

Service de Chirurgie Maxillo-faciale et Réparatrice, CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Nawfal Mellas (N)

Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

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Classifications MeSH