Post-translational acylation controls the folding and functions of the CyaA RTX toxin.

Acylation Adenylate Cyclase Toxin / chemistry Amino Acid Sequence Anilino Naphthalenesulfonates / pharmacology Animals Bordetella pertussis / genetics Erythrocytes / drug effects Hydrophobic and Hydrophilic Interactions Lysine / chemistry Protein Conformation Protein Domains Protein Folding Protein Processing, Post-Translational Protein Stability Recombinant Proteins / chemistry Sheep Structure-Activity Relationship Tandem Mass Spectrometry Urea
adenylate cyclase bordetella pertussis calcium-binding protein post-translational modification protein folding

Journal

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484

Informations de publication

Date de publication:
09 2019
Historique:
pubmed: 22 6 2019
medline: 2 6 2020
entrez: 22 6 2019
Statut: ppublish

Résumé

The adenylate cyclase (CyaA) toxin is a major virulence factor of

Identifiants

DOI: 10.1096/fj.201802442RR PMID: 31226003
pubmed: 31226003
doi: 10.1096/fj.201802442RR
doi:

Substances chimiques

8-anilino-1-naphthalenesulfonic acid 0
Adenylate Cyclase Toxin 0
Anilino Naphthalenesulfonates 0
Recombinant Proteins 0
Urea 8W8T17847W
Lysine K3Z4F929H6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10065-10076

Auteurs

Darragh P O'Brien (DP)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

Sara E Cannella (SE)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

Alexis Voegele (A)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.
Université Paris Diderot Paris VII, Sorbonne Paris Cité, Paris, France.

Dorothée Raoux-Barbot (D)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

Marilyne Davi (M)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

Thibaut Douché (T)

Institut Pasteur, Proteomics Platform, Mass Spectrometry for Biology Unit, USR CNRS 2000, Paris, France.

Mariette Matondo (M)

Institut Pasteur, Proteomics Platform, Mass Spectrometry for Biology Unit, USR CNRS 2000, Paris, France.

Sébastien Brier (S)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.
Biological NMR Technical Platform, Center for Technological Resources and Research, UMR CNRS 3528, Paris, France.

Daniel Ladant (D)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

Alexandre Chenal (A)

Institut Pasteur, Chemistry and Structural Biology Department, UMR CNRS 3528, Paris, France.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Acylation › Post-translational acylation controls the...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Facteurs de virulence › Facteurs de virulence des Bordetella › Toxine d'adénylate cyclase › Post-translational acylation controls the...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › Post-translational acylation controls the...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Naphtalènes › Naphtalènesulfonates › Anilino-naphtalènesulfonates › Post-translational acylation controls the...
questionsmedicales.fr › Eucaryotes › Animaux › Post-translational acylation controls the...
questionsmedicales.fr › Bactéries › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella pertussis › Post-translational acylation controls the...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Sang › Cellules sanguines › Érythrocytes › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › Post-translational acylation controls the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Lysine › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Pliage des protéines › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Modification traductionnelle des protéines › Maturation post-traductionnelle des protéines › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Stabilité protéique › Post-translational acylation controls the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines recombinantes › Post-translational acylation controls the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Ruminants › Ovis › Post-translational acylation controls the...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Post-translational acylation controls the...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › Post-translational acylation controls the...
questionsmedicales.fr › Composés chimiques organiques › Amides › Urée › Post-translational acylation controls the...