A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report "Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention".
FRACTURE PREVENTION
OSTEOPOROSIS
OSTEOPOROSIS DRUG THERAPY
Journal
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
ISSN: 1523-4681
Titre abrégé: J Bone Miner Res
Pays: United States
ID NLM: 8610640
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
25
04
2019
revised:
18
06
2019
accepted:
22
06
2019
pubmed:
27
6
2019
medline:
23
9
2020
entrez:
26
6
2019
Statut:
ppublish
Résumé
The public health implications of osteoporosis are enormous but the disease remains underdiagnosed and undertreated. In October 2018, the National Institutes of Health (NIH) convened a Pathways to Prevention (P2P) Workshop entitled "Appropriate Use of Drug Therapies for Osteoporotic Fracture Prevention" designed to identify research gaps, suggest future research opportunities, and advance the field through an evidence-based assessment. By design, the P2P report focused on "gaps" in our knowledge base. Unfortunately, however, the report did not sufficiently acknowledge the current evidence that unequivocally demonstrates the therapeutic efficacy of existing pharmacologic therapies for osteoporosis, which has the potential to exacerbate the current crises in osteoporosis diagnosis and treatment. © 2019 American Society for Bone and Mineral Research.
Identifiants
pubmed: 31237962
doi: 10.1002/jbmr.3823
pmc: PMC7082897
mid: NIHMS1573495
doi:
Substances chimiques
Bone Density Conservation Agents
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1549-1551Subventions
Organisme : NIAMS NIH HHS
ID : R01 AR027065
Pays : United States
Informations de copyright
© 2019 American Society for Bone and Mineral Research.
Références
J Clin Endocrinol Metab. 2012 Sep;97(9):3097-106
pubmed: 22723322
Bone. 2013 Dec;57(2):423-8
pubmed: 24063946
JAMA. 2009 Oct 14;302(14):1573-9
pubmed: 19826027
Ann Intern Med. 2019 Jul 2;171(1):51-57
pubmed: 31009943
J Bone Miner Res. 2014 Sep;29(9):1929-37
pubmed: 24535775
J Bone Miner Res. 2007 Mar;22(3):465-75
pubmed: 17144789
N Engl J Med. 2012 Nov;367(18):1714-23
pubmed: 23113482
J Bone Miner Res. 2016 Dec 29;32(3):424-430
pubmed: 28099754
J Bone Miner Metab. 2012 May;30(3):321-5
pubmed: 21938382
Osteoporos Int. 2011 May;22(5):1277-88
pubmed: 21461721
Horm Metab Res. 2018 Oct;50(10):738-746
pubmed: 30312984
Osteoporos Int. 2018 Mar;29(3):717-722
pubmed: 29282482
N Engl J Med. 2016 May 26;374(21):2096-7
pubmed: 27223157
J Bone Miner Res. 2014 Nov;29(11):2520-6
pubmed: 24771492