A Novel Nutritional Index Serves as A Useful Prognostic Indicator in Cardiac Critical Patients Requiring Mechanical Circulatory Support.
Aged
Aged, 80 and over
Biomarkers
/ blood
Body Weight
Cholesterol
/ blood
Critical Illness
Extracorporeal Membrane Oxygenation
/ adverse effects
Female
Heart Diseases
/ diagnosis
Heart-Assist Devices
Hemodynamics
Humans
Intra-Aortic Balloon Pumping
/ adverse effects
Japan
Male
Middle Aged
Nutrition Assessment
Nutritional Status
Predictive Value of Tests
Recovery of Function
Registries
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
Triglycerides
/ blood
intensive care unit
mechanical circulatory support
nutritional index
prognostic indicator
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
24 Jun 2019
24 Jun 2019
Historique:
received:
27
05
2019
revised:
18
06
2019
accepted:
20
06
2019
entrez:
27
6
2019
pubmed:
27
6
2019
medline:
7
1
2020
Statut:
epublish
Résumé
A poor nutritional status has been gathering intense clinical interest recently as it has been suggested to associate with adverse outcomes in patients in the intensive care unit (ICU). However, there is still no established nutritional index dominantly used in clinical practice. We have previously proposed a novel nutritional index, which can be calculated using serum levels of triglycerides, total cholesterol, and body weight (TCBI). In this study, to expand the application of TCBI for critical patients, we investigated the usefulness of TCBI to predict prognosis in hemodynamically unstable patients with percutaneously implantable mechanical circulatory support (MCS) devices in the ICU. This is a retrospective analysis of a multicenter registry consisting of three Juntendo University hospitals in Japan involving patients who received MCS devices, including intra-aortic balloon pumping (IABP) with or without veno-arterial extracorporeal membrane oxygenation (VA-ECMO), between 2012 and 2016 ( Spearman's correlation coefficient between TCBI and the geriatric nutritional risk index (GNRI) was 0.44 ( A novel and simple to calculate nutritional index, TCBI, can be applicable as a prognostic indicator in hemodynamically unstable patients requiring MCS devices.
Sections du résumé
BACKGROUND
BACKGROUND
A poor nutritional status has been gathering intense clinical interest recently as it has been suggested to associate with adverse outcomes in patients in the intensive care unit (ICU). However, there is still no established nutritional index dominantly used in clinical practice. We have previously proposed a novel nutritional index, which can be calculated using serum levels of triglycerides, total cholesterol, and body weight (TCBI). In this study, to expand the application of TCBI for critical patients, we investigated the usefulness of TCBI to predict prognosis in hemodynamically unstable patients with percutaneously implantable mechanical circulatory support (MCS) devices in the ICU.
PATIENTS AND METHODS
METHODS
This is a retrospective analysis of a multicenter registry consisting of three Juntendo University hospitals in Japan involving patients who received MCS devices, including intra-aortic balloon pumping (IABP) with or without veno-arterial extracorporeal membrane oxygenation (VA-ECMO), between 2012 and 2016 (
RESULTS
RESULTS
Spearman's correlation coefficient between TCBI and the geriatric nutritional risk index (GNRI) was 0.44 (
CONCLUSION
CONCLUSIONS
A novel and simple to calculate nutritional index, TCBI, can be applicable as a prognostic indicator in hemodynamically unstable patients requiring MCS devices.
Identifiants
pubmed: 31238536
pii: nu11061420
doi: 10.3390/nu11061420
pmc: PMC6627834
pii:
doi:
Substances chimiques
Biomarkers
0
Triglycerides
0
Cholesterol
97C5T2UQ7J
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Références
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