Evaluation of the information given to patients undergoing total pharyngolaryngectomy and quality of life: a prospective multicentric study.


Journal

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 13 03 2019
accepted: 10 06 2019
pubmed: 27 6 2019
medline: 30 11 2019
entrez: 27 6 2019
Statut: ppublish

Résumé

Providing cancer patients with adequate information is essential to their confidence and satisfaction regarding medical care. The aims of this study were to evaluate the information given to patients undergoing total pharyngolaryngectomy (TPL) as well as the evolution and predictors of patient quality of life (QoL). We conducted a prospective multicentric study on patients undergoing TPL for a locally advanced laryngeal/hypopharyngeal cancer. All patients completed the EORTC QLQ-INFO25, QLQ-C30, and QLQ-H&N35 questionnaires, before and after surgery. This study enrolled 46 patients. Between the pre- and post-therapeutic periods, we observed no significant changes in the global QLQ-INFO25 and QLQ-C30 scores. However, we found a significant deterioration in 4 QLQ-INFO25 scales/items and in social functioning, as well as an increase of sense, speech, and social contact problems. N-stage and professional activity were significant predictors of preoperative QLQ-INFO25 scores. Younger age was significantly associated with financial difficulties, whereas professional activity and lower education level were significant predictors of xerostomia and swallowing problems, respectively. In patients undergoing TPL, we observed significant changes in QLQ-INFO25 scores between the pre- and post-treatment periods and, particularly, a deterioration of patient satisfaction with the information received. Several clinical factors were identified as significant predictors of QLQ-INFO25 and QoL scores.

Sections du résumé

BACKGROUND BACKGROUND
Providing cancer patients with adequate information is essential to their confidence and satisfaction regarding medical care. The aims of this study were to evaluate the information given to patients undergoing total pharyngolaryngectomy (TPL) as well as the evolution and predictors of patient quality of life (QoL).
METHODS METHODS
We conducted a prospective multicentric study on patients undergoing TPL for a locally advanced laryngeal/hypopharyngeal cancer. All patients completed the EORTC QLQ-INFO25, QLQ-C30, and QLQ-H&N35 questionnaires, before and after surgery.
RESULTS RESULTS
This study enrolled 46 patients. Between the pre- and post-therapeutic periods, we observed no significant changes in the global QLQ-INFO25 and QLQ-C30 scores. However, we found a significant deterioration in 4 QLQ-INFO25 scales/items and in social functioning, as well as an increase of sense, speech, and social contact problems. N-stage and professional activity were significant predictors of preoperative QLQ-INFO25 scores. Younger age was significantly associated with financial difficulties, whereas professional activity and lower education level were significant predictors of xerostomia and swallowing problems, respectively.
CONCLUSION CONCLUSIONS
In patients undergoing TPL, we observed significant changes in QLQ-INFO25 scores between the pre- and post-treatment periods and, particularly, a deterioration of patient satisfaction with the information received. Several clinical factors were identified as significant predictors of QLQ-INFO25 and QoL scores.

Identifiants

pubmed: 31240456
doi: 10.1007/s00405-019-05513-6
pii: 10.1007/s00405-019-05513-6
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

2531-2539

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Auteurs

Alexandre Bozec (A)

Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, 06103, Nice, France. alexandre.bozec@nice.unicancer.fr.

Philippe Schultz (P)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Strasbourg, Strasbourg, France.

Jocelyn Gal (J)

Department of Statistics, Centre Antoine Lacassagne, Nice, France.

Emmanuel Chamorey (E)

Department of Statistics, Centre Antoine Lacassagne, Nice, France.

Yann Chateau (Y)

Department of Statistics, Centre Antoine Lacassagne, Nice, France.

Olivier Dassonville (O)

Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, 06103, Nice, France.

Gilles Poissonnet (G)

Institut Universitaire de la Face et du Cou, 31 avenue de Valombrose, 06103, Nice, France.

Frédéric Peyrade (F)

Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.

Esma Saada (E)

Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.

Joël Guigay (J)

Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.

Karen Benezery (K)

Department of Radiotherapy, Centre Antoine Lacassagne, Nice, France.

Axel Leysalle (A)

Department of Radiotherapy, Centre Antoine Lacassagne, Nice, France.

Laure Santini (L)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Marseille, Marseille, France.

Antoine Giovanni (A)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Marseille, Marseille, France.

Lila Messaoudi (L)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Strasbourg, Strasbourg, France.

Nicolas Fakhry (N)

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Marseille, Marseille, France.

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Classifications MeSH