Clonidine suppression testing for pheochromocytoma in neurofibromatosis type 1.
adrenal disorders
neuro genetics
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
25 Jun 2019
25 Jun 2019
Historique:
entrez:
28
6
2019
pubmed:
28
6
2019
medline:
17
1
2020
Statut:
epublish
Résumé
Compared with the general population, rates of pheochromocytoma are higher in neurofibromatosis type 1 (NF1) patients. However, pheochromocytoma testing is often plagued by false positive results. Here we present a patient with NF1, elevated urinary metanephrine levels, and an indeterminate adrenal nodule. Clonidine suppression testing aided diagnosis and led to definitive surgical treatment that confirmed a pheochromocytoma. Pheochromocytoma screening and clonidine suppression testing can both aid in the evaluation for catecholamine-secreting tumours.
Identifiants
pubmed: 31243023
pii: 12/6/e228263
doi: 10.1136/bcr-2018-228263
pmc: PMC6605898
pii:
doi:
Substances chimiques
Adrenergic alpha-2 Receptor Agonists
0
Metanephrine
5001-33-2
Clonidine
MN3L5RMN02
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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