Meroterpenoids with BACE1 Inhibitory Activity from the Fruiting Body of

Amyloid Precursor Protein Secretases / antagonists & inhibitors Aspartic Acid Endopeptidases / antagonists & inhibitors Basidiomycota / chemistry Carbon-13 Magnetic Resonance Spectroscopy Fruiting Bodies, Fungal / chemistry Inhibitory Concentration 50 Proton Magnetic Resonance Spectroscopy Spectrometry, Mass, Electrospray Ionization Terpenes / chemistry

Journal

Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882

Informations de publication

Date de publication:
26 07 2019
Historique:
pubmed: 28 6 2019
medline: 22 10 2020
entrez: 28 6 2019
Statut: ppublish

Résumé

BACE1 inhibitory activity-guided fractionation of an extract of the fruiting body of

Identifiants

DOI: 10.1021/acs.jnatprod.8b01092 PMID: 31244141
pubmed: 31244141
doi: 10.1021/acs.jnatprod.8b01092
doi:

Substances chimiques

Terpenes 0
Amyloid Precursor Protein Secretases EC 3.4.-
Aspartic Acid Endopeptidases EC 3.4.23.-
BACE1 protein, human EC 3.4.23.46

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1797-1801

Auteurs

Genki Yatsu (G)

Department of Pharmacognosy and Phytochemistry , Meiji Pharmaceutical University , Noshio 2-522-1 , Kiyose-shi , Tokyo 204-8588 , Japan.

Yoshihiro Kino (Y)

Department of Bioinformatics and Molecular Neuropathology , Meiji Pharmaceutical University , 2-522-1, Noshio , Kiyose-shi , Tokyo 204-8588 , Japan.

Hiroaki Sasaki (H)

School of Pharmacy , Shujitsu University , Nishigawara 1-6-1, Naka-ku , Okayama-shi , Okayama 703-8516 , Japan.

Jun-Ichi Satoh (JI)

Department of Bioinformatics and Molecular Neuropathology , Meiji Pharmaceutical University , 2-522-1, Noshio , Kiyose-shi , Tokyo 204-8588 , Japan.

Kaoru Kinoshita (K)

Department of Pharmacognosy and Phytochemistry , Meiji Pharmaceutical University , Noshio 2-522-1 , Kiyose-shi , Tokyo 204-8588 , Japan.

Kiyotaka Koyama (K)

Department of Pharmacognosy and Phytochemistry , Meiji Pharmaceutical University , Noshio 2-522-1 , Kiyose-shi , Tokyo 204-8588 , Japan.
ORCID: 0000-0001-9884-0080

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Endopeptidases › Amyloid precursor protein secretases › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Endopeptidases › Aspartic acid endopeptidases › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Eucaryotes › Champignons › Basidiomycota › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie par résonance magnétique du carbone-13 › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Structures fongiques › Corps fructifères de champignon › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Concentration inhibitrice 50 › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie par résonance magnétique du proton › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse ESI › Meroterpenoids with BACE1 Inhibitory Activity...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Meroterpenoids with BACE1 Inhibitory Activity...