Growth, Feeding Tolerance and Metabolism in Extreme Preterm Infants under an Exclusive Human Milk Diet.
Age Factors
Austria
Birth Weight
Bottle Feeding
/ adverse effects
Child Development
Enterocolitis, Necrotizing
/ etiology
Gestational Age
Humans
Infant Formula
/ adverse effects
Infant Nutritional Physiological Phenomena
Infant, Extremely Low Birth Weight
/ growth & development
Infant, Extremely Premature
/ growth & development
Infant, Newborn
Milk, Human
Nutritional Status
Nutritive Value
Retrospective Studies
Time Factors
ELBW-infants
exclusive human milk diet
feeding tolerance
fortification of human milk
growth velocity
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
26 Jun 2019
26 Jun 2019
Historique:
received:
06
05
2019
revised:
18
06
2019
accepted:
24
06
2019
entrez:
29
6
2019
pubmed:
30
6
2019
medline:
8
1
2020
Statut:
epublish
Résumé
For preterm infants, human milk (HM) has to be fortified to cover their enhanced nutritional requirements and establish adequate growth. Most HM fortifiers are based on bovine protein sources (BMF). An HM fortifier based on human protein sources (HMF) has become available in the last few years. The aim of this study is to investigate the impact of an HMF versus BMF on growth in extremely low birth weight (ELBW, <1000 g) infants. This was a retrospective, controlled, multicenter cohort study in infants with a birthweight below 1000 g. The HMF group received an exclusive HM diet up to 32+0 weeks of gestation and was changed to BMF afterwards. The BMF group received HM+BMF from fortifier introduction up to 37+0 weeks. 192 extremely low birth weight (ELBW)-infants were included (HMF Results from this study do not support the superiority of HFM over BMF in ELBW infants.
Sections du résumé
BACKGROUND
BACKGROUND
For preterm infants, human milk (HM) has to be fortified to cover their enhanced nutritional requirements and establish adequate growth. Most HM fortifiers are based on bovine protein sources (BMF). An HM fortifier based on human protein sources (HMF) has become available in the last few years. The aim of this study is to investigate the impact of an HMF versus BMF on growth in extremely low birth weight (ELBW, <1000 g) infants.
METHODS
METHODS
This was a retrospective, controlled, multicenter cohort study in infants with a birthweight below 1000 g. The HMF group received an exclusive HM diet up to 32+0 weeks of gestation and was changed to BMF afterwards. The BMF group received HM+BMF from fortifier introduction up to 37+0 weeks.
RESULTS
RESULTS
192 extremely low birth weight (ELBW)-infants were included (HMF
CONCLUSION
CONCLUSIONS
Results from this study do not support the superiority of HFM over BMF in ELBW infants.
Identifiants
pubmed: 31248006
pii: nu11071443
doi: 10.3390/nu11071443
pmc: PMC6683272
pii:
doi:
Types de publication
Comparative Study
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Am J Respir Crit Care Med. 2001 Jun;163(7):1723-9
pubmed: 11401896
Behav Brain Res. 1992 Jul 31;49(1):1-6
pubmed: 1388792
BMC Pediatr. 2003 Dec 16;3:13
pubmed: 14678563
Cochrane Database Syst Rev. 2004;(1):CD000343
pubmed: 14973953
Arch Ophthalmol. 2005 Jul;123(7):991-9
pubmed: 16009843
J Pediatr Gastroenterol Nutr. 2005 Nov;41 Suppl 2:S1-87
pubmed: 16254497
Pediatrics. 2005 Dec;116(6):1466-73
pubmed: 16322172
Neonatal Netw. 2007 Sep-Oct;26(5):335-51
pubmed: 17926662
J Pediatr Gastroenterol Nutr. 2010 Jan;50(1):85-91
pubmed: 19881390
J Pediatr. 2010 Apr;156(4):562-7.e1
pubmed: 20036378
Curr Opin Clin Nutr Metab Care. 2010 May;13(3):314-20
pubmed: 20179589
Pediatr Res. 2011 Jun;69(6):522-9
pubmed: 21378596
Adv Neonatal Care. 2011 Jun;11(3):149-54
pubmed: 21730906
Pediatrics. 2012 Mar;129(3):e827-41
pubmed: 22371471
Neonatology. 2012;102(4):276-81
pubmed: 22922675
Cochrane Database Syst Rev. 2013 Feb 28;(2):CD004866
pubmed: 23450556
J Pediatr. 2013 Dec;163(6):1592-1595.e1
pubmed: 23968744
BMC Res Notes. 2013 Nov 13;6:459
pubmed: 24220185
J Pediatr. 2014 Nov;165(5):915-20
pubmed: 25130571
J Int Med Res. 2015 Jun;43(3):279-89
pubmed: 25956156
Pediatrics. 2015 Jul;136(1):e84-92
pubmed: 26101360
Cochrane Database Syst Rev. 2015 Oct 15;(10):CD001241
pubmed: 26469124
J Perinatol. 2016 Mar;36(3):216-20
pubmed: 26562370
Breastfeed Med. 2016 Mar;11(2):70-4
pubmed: 26789484
Am J Perinatol. 2017 Jan;34(2):130-137
pubmed: 27322667
J Perinatol. 2017 Jul;37(7):827-833
pubmed: 28358382
Am J Clin Nutr. 2017 Sep;106(3):821-830
pubmed: 28659297
Hong Kong Med J. 2017 Aug;23(4):381-6
pubmed: 28684649
Nutr Clin Pract. 2018 Oct;33(5):671-678
pubmed: 29451716
Breastfeed Med. 2018 Jul/Aug;13(6):408-411
pubmed: 29877722
Am J Clin Nutr. 2018 Jul 1;108(1):108-116
pubmed: 29878061
Clin Nutr. 2018 Dec;37(6 Pt B):2309-2314
pubmed: 30078715
Clin Nutr. 2018 Dec;37(6 Pt B):2315-2323
pubmed: 30100107
Pediatrics. 1977 Oct;60(4):519-30
pubmed: 333369
Curr Probl Pediatr. 1987 Apr;17(4):213-88
pubmed: 3556038
Pediatrics. 1985 May;75(5):976-86
pubmed: 3921937