The occupations at increased risk of COPD: analysis of lifetime job-histories in the population-based UK Biobank Cohort.
Adult
Aged
Biological Specimen Banks
Female
Forced Expiratory Volume
Humans
Male
Middle Aged
Occupational Diseases
/ epidemiology
Occupational Exposure
/ adverse effects
Occupations
/ classification
Poisson Distribution
Prevalence
Prospective Studies
Pulmonary Disease, Chronic Obstructive
/ epidemiology
Risk Factors
Spirometry
State Medicine
United Kingdom
/ epidemiology
Journal
The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
25
01
2019
accepted:
21
04
2019
pubmed:
30
6
2019
medline:
17
9
2020
entrez:
29
6
2019
Statut:
epublish
Résumé
Occupational exposures are important, preventable causes of chronic obstructive pulmonary disease (COPD). Identification of COPD high-risk jobs is key to focus preventive strategies, but a definitive job-list is unavailable.We addressed this issue by evaluating the association of lifetime job-histories and lung function data in the population-based UK Biobank cohort, whose unprecedented sample size allowed analyses restricted to never-smokers to rule out the most important confounder, tobacco smoking. COPD was spirometrically defined as forced expiratory volume in 1 s/forced vital capacity ratio below the lower limit of normal. Lifetime job-histories were collected
Identifiants
pubmed: 31248951
pii: 13993003.00186-2019
doi: 10.1183/13993003.00186-2019
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Research Council
ID : MR/L01341X/1
Pays : United Kingdom
Informations de copyright
The content of this work is copyright of the authors or their employers. Design and branding is copyright ©ERS 2019.
Déclaration de conflit d'intérêts
Conflict of interest: S. De Matteis has nothing to disclose. Conflict of interest: D. Jarvis has nothing to disclose. Conflict of interest: A. Darnton has nothing to disclose. Conflict of interest: S. Hutchings has nothing to disclose. Conflict of interest: S. Sadhra has nothing to disclose. Conflict of interest: D. Fishwick has nothing to disclose. Conflict of interest: L. Rushton has nothing to disclose. Conflict of interest: P. Cullinan has nothing to disclose.