Benzophenone Photoreactivity in a Lipid Bilayer To Probe Peptide/Membrane Interactions: Simple System, Complex Information.
Amino Acid Sequence
Benzophenones
/ chemistry
Cell-Penetrating Peptides
/ chemistry
Cholesterol
/ chemistry
Cross-Linking Reagents
/ chemistry
Fatty Acids
/ analysis
Lipid Bilayers
/ chemistry
Oxidation-Reduction
/ radiation effects
Phospholipids
/ chemistry
Tandem Mass Spectrometry
Ultraviolet Rays
Journal
Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536
Informations de publication
Date de publication:
16 07 2019
16 07 2019
Historique:
pubmed:
30
6
2019
medline:
26
9
2020
entrez:
29
6
2019
Statut:
ppublish
Résumé
Affinity photo-cross-linking coupled to mass spectrometry, using benzophenone (Bzp)-functionalized peptides, was used to study the noncovalent interactions of cell-penetrating peptides and lipid membranes. Using biomimetic lipid vesicles composed of saturated and unsaturated negatively charged lipids, DMPG (14:0), DPPG (16:0), DOPG (18:1
Identifiants
pubmed: 31251038
doi: 10.1021/acs.analchem.9b01584
doi:
Substances chimiques
Benzophenones
0
Cell-Penetrating Peptides
0
Cross-Linking Reagents
0
Fatty Acids
0
Lipid Bilayers
0
Phospholipids
0
benzophenone
701M4TTV9O
Cholesterol
97C5T2UQ7J
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM