C57BL/6 congenic mouse NRAS
Animals
Antineoplastic Combined Chemotherapy Protocols
/ pharmacology
Benzimidazoles
/ pharmacology
Cell Line, Tumor
Cell Proliferation
/ drug effects
Cell Shape
/ drug effects
Heterocyclic Compounds, 3-Ring
/ pharmacology
Melanocytes
/ drug effects
Melanoma
/ pathology
Mice, Inbred C57BL
Mitogen-Activated Protein Kinase Kinases
/ antagonists & inhibitors
Models, Biological
Monomeric GTP-Binding Proteins
/ genetics
Protein Kinase Inhibitors
/ pharmacology
Proto-Oncogene Proteins c-akt
/ antagonists & inhibitors
Signal Transduction
/ drug effects
MK-2206 2HCl
PD-0325901
S6
binimetinib
mouse model
Journal
Pigment cell & melanoma research
ISSN: 1755-148X
Titre abrégé: Pigment Cell Melanoma Res
Pays: England
ID NLM: 101318927
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
18
01
2019
revised:
30
05
2019
accepted:
25
06
2019
pubmed:
30
6
2019
medline:
27
6
2020
entrez:
29
6
2019
Statut:
ppublish
Résumé
RAS is frequently mutated in various tumors and known to be difficult to target. NRAS
Substances chimiques
Benzimidazoles
0
Heterocyclic Compounds, 3-Ring
0
MK 2206
0
Protein Kinase Inhibitors
0
binimetinib
181R97MR71
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
Mitogen-Activated Protein Kinase Kinases
EC 2.7.12.2
Monomeric GTP-Binding Proteins
EC 3.6.5.2
Nras protein, mouse
EC 3.6.5.2
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
829-841Subventions
Organisme : NCI NIH HHS
ID : CA16672
Pays : United States
Informations de copyright
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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