High-speed atomic force microscopy.

Microscopy, Atomic Force / methods Molecular Dynamics Simulation Molecular Imaging / methods Proteins / chemistry

Journal

Current opinion in chemical biology
ISSN: 1879-0402
Titre abrégé: Curr Opin Chem Biol
Pays: England
ID NLM: 9811312

Informations de publication

Date de publication:
08 2019
Historique:
received: 15 12 2018
revised: 23 04 2019
accepted: 13 05 2019
pubmed: 30 6 2019
medline: 3 4 2020
entrez: 30 6 2019
Statut: ppublish

Résumé

High-speed atomic force microscopy (HS-AFM) is a unique tool for molecular imaging. It can directly visualize protein molecules during their functional activity at high spatiotemporal resolution, without a marker being attached to the molecules. Molecular dynamics filmed with HS-AFM can provide mechanistic insights into the functional molecular processes that are hard to be attained with other approaches. In this mini review, I highlight some of recent relevant studies of proteins by HS-AFM imaging after brief descriptions of AFM and HS-AFM.

Identifiants

DOI: 10.1016/j.cbpa.2019.05.010 PMID: 31254806
pubmed: 31254806
pii: S1367-5931(18)30199-6
doi: 10.1016/j.cbpa.2019.05.010
pii:
doi:

Substances chimiques

Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

105-112

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Toshio Ando (T)

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. Electronic address: tando@staff.kanazawa-u.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Microscopie à sonde à balayage › Microscopie à force atomique › High-speed atomic force microscopy.
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › High-speed atomic force microscopy.
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Imagerie moléculaire › High-speed atomic force microscopy.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › High-speed atomic force microscopy.