Factors associated with exercise capacity in patients with a systemic right ventricle.
Cardiopulmonary exercise test
Congenital heart disease
NYHA functional class
Systemic right ventricle
Journal
International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291
Informations de publication
Date de publication:
01 10 2019
01 10 2019
Historique:
received:
16
03
2019
revised:
21
05
2019
accepted:
12
06
2019
pubmed:
2
7
2019
medline:
13
6
2020
entrez:
2
7
2019
Statut:
ppublish
Résumé
Systemic right ventricle (RV) is a rare and complex congenital heart disease (CHD). Patients with a systemic RV present with a significant decrease of their exercise capacity. We aimed at identifying clinical and paraclinical factors associated with maximum oxygen uptake (VO2 This multicentre cross-sectional study was performed in 2017 in three French tertiary care CHD centres. Adult patients with a D-transposition of the great artery (d-TGA) or a congenitally corrected TGA (cc-TGA) were included. Demographic, clinical, laboratory and imaging data were collected. Univariate and multivariate analyses were performed to identify predictors of impaired VO2 A total of 111 patients were included in the study (85% d-TGA, median age 37.2 ± 8.2 years). Most patients presented with impaired physical capacity (mean VO2 NYHA functional class and RV function are predictors of impaired exercise capacity in adult patients with systemic RV.
Sections du résumé
BACKGROUND
Systemic right ventricle (RV) is a rare and complex congenital heart disease (CHD). Patients with a systemic RV present with a significant decrease of their exercise capacity. We aimed at identifying clinical and paraclinical factors associated with maximum oxygen uptake (VO2
METHODS
This multicentre cross-sectional study was performed in 2017 in three French tertiary care CHD centres. Adult patients with a D-transposition of the great artery (d-TGA) or a congenitally corrected TGA (cc-TGA) were included. Demographic, clinical, laboratory and imaging data were collected. Univariate and multivariate analyses were performed to identify predictors of impaired VO2
RESULTS
A total of 111 patients were included in the study (85% d-TGA, median age 37.2 ± 8.2 years). Most patients presented with impaired physical capacity (mean VO2
CONCLUSION
NYHA functional class and RV function are predictors of impaired exercise capacity in adult patients with systemic RV.
Identifiants
pubmed: 31256996
pii: S0167-5273(19)31187-8
doi: 10.1016/j.ijcard.2019.06.030
pii:
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
230-235Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.