[GEFPICS' guidelines for management of breast cancer tissue samples in the neoadjuvant setting].
Recommandations du GEFPICS pour la prise en charge des prélèvements dans le cadre du traitement néoadjuvant du cancer du sein.
Biomarkers, Tumor
Biopsy
/ methods
Breast
/ pathology
Breast Neoplasms
/ chemistry
Chemotherapy, Adjuvant
/ standards
Drug Screening Assays, Antitumor
Female
France
Humans
Lymph Nodes
/ drug effects
Medical Records
/ standards
Microscopy
Neoadjuvant Therapy
Neoplasm, Residual
/ pathology
Prognosis
Sentinel Lymph Node Biopsy
/ methods
Specimen Handling
/ methods
Treatment Outcome
Tumor Burden
/ drug effects
Breast cancer
Cancer du sein
Guidelines
Neoadjuvant
Néoadjuvant
Pathological response
Prélèvement
Recommandations
Réponse pathologique
Tissue sample
Journal
Annales de pathologie
ISSN: 0242-6498
Titre abrégé: Ann Pathol
Pays: France
ID NLM: 8106337
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
30
11
2018
revised:
27
03
2019
accepted:
13
04
2019
pubmed:
2
7
2019
medline:
10
5
2020
entrez:
2
7
2019
Statut:
ppublish
Résumé
Neoadjuvant therapy is an increasing treatment option in the management of breast cancer. The tumor response to neoadjuvant therapy, especially the pathological complete response, is a validated endpoint frequently used in clinical trials. However, there is still a lack of standardization for the surgical specimen management in the neoadjuvant setting. This leads to heterogeneity in the specimen handling and might lead to significant bias for the prognostic assessment of patients or in clinical trials. The GEFPICS group, composed of expert breast cancer pathologists, herein presents guidelines for the management of breast and axillary specimen before treatment (management of biopsy, items of the pathological report) and after neoadjuvant therapy (specimen handling, histological assessment of response, items of the pathological report and response grading systems).
Identifiants
pubmed: 31257035
pii: S0242-6498(19)30089-6
doi: 10.1016/j.annpat.2019.04.004
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Practice Guideline
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
383-398Informations de copyright
Copyright © 2019 Elsevier Masson SAS. All rights reserved.