ECMM CandiReg-A ready to use platform for outbreaks and epidemiological studies.
Candidemia
epidemiology
invasive candidiasis
invasive fungal infection
outbreak
Journal
Mycoses
ISSN: 1439-0507
Titre abrégé: Mycoses
Pays: Germany
ID NLM: 8805008
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
24
05
2019
accepted:
28
06
2019
pubmed:
5
7
2019
medline:
29
1
2020
entrez:
5
7
2019
Statut:
ppublish
Résumé
Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance. Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance. CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser. CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform. CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.
Sections du résumé
BACKGROUND
BACKGROUND
Recent outbreaks of Candida auris further exemplify that invasive Candida infections are a substantial threat to patients and healthcare systems. Even short treatment delays are associated with higher mortality rates. Epidemiological shifts towards more resistant Candida spp. require careful surveillance.
OBJECTIVES
OBJECTIVE
Triggered by the emergence of C auris and by increasing antifungal resistance rates the European Confederation of Medical Mycology developed an international Candida Registry (FungiScope™ CandiReg) to allow contemporary multinational surveillance.
METHODS
METHODS
CandiReg serves as platform for international cooperation to enhance research regarding invasive Candida infections. CandiReg uses the General Data Protection Regulation compliant data platform ClinicalSurveys.net that holds the electronic case report forms (eCRF). Data entry is supported via an interactive macro created by the software that can be accessed via any Internet browser.
RESULTS
RESULTS
CandiReg provides an eCRF for invasive Candida infections that can be used for a variety of studies from cohort studies on attributable mortality to evaluations of guideline adherence, offering to the investigators of the 28 ECMM member countries the opportunity to document their cases of invasive Candida infection. CandiReg allows the monitoring of epidemiology of invasive Candida infections, including monitoring of multinational outbreaks. Here, we describe the structure and management of the CandiReg platform.
CONCLUSION
CONCLUSIONS
CandiReg supports the collection of clinical information and isolates to improve the knowledge on epidemiology and eventually to improve management of invasive Candida infections. CandiReg promotes international collaboration, improving the availability and quality of evidence on invasive Candida infection and contributes to improved patient management.
Identifiants
pubmed: 31271702
doi: 10.1111/myc.12963
pmc: PMC7614793
mid: EMS178619
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
920-927Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 101873
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N006364/1
Pays : United Kingdom
Informations de copyright
© 2019 Blackwell Verlag GmbH.
Références
Clin Microbiol Infect. 2012 Dec;18 Suppl 7:9-18
pubmed: 23137134
Mycoses. 2018 May;61(5):326-330
pubmed: 29325218
Clin Microbiol Infect. 2012 Dec;18 Suppl 7:53-67
pubmed: 23137137
Int J Antimicrob Agents. 2014 Jan;43(1):78-81
pubmed: 24182454
Clin Infect Dis. 2003 Nov 1;37(9):1172-7
pubmed: 14557960
Clin Microbiol Infect. 2019 Oct;25(10):1200-1212
pubmed: 31039444
Arch Intern Med. 1988 Dec;148(12):2642-5
pubmed: 3196127
Eur J Clin Microbiol Infect Dis. 2018 Aug;37(8):1563-1571
pubmed: 29948362
Clin Microbiol Infect. 2015 Jan;21(1):87.e1-87.e10
pubmed: 25636940
Clin Infect Dis. 2016 Feb 15;62(4):e1-50
pubmed: 26679628
N Engl J Med. 2015 Oct 8;373(15):1445-56
pubmed: 26444731
Mycoses. 2018 Jul;61(7):498-505
pubmed: 29655180
Mycoses. 2020 Dec;63(12):1373-1381
pubmed: 32885534
Emerg Microbes Infect. 2018 Mar 29;7(1):43
pubmed: 29593275
Mycoses. 2017 Aug;60(8):508-516
pubmed: 28730644
Haematologica. 2017 Mar;102(3):433-444
pubmed: 28011902
Antimicrob Resist Infect Control. 2016 Oct 19;5:35
pubmed: 27777756
Mycoses. 2018 Jan;61(1):48-52
pubmed: 28872711
Eur J Clin Microbiol Infect Dis. 2004 Apr;23(4):317-22
pubmed: 15029512
Mycoses. 2018 Nov;61(11):885-894
pubmed: 30086186
Front Microbiol. 2018 Jun 22;9:1381
pubmed: 29988394
Mycoses. 2018 Sep;61(9):674-680
pubmed: 29738604
Intensive Care Med. 2014 Sep;40(9):1303-12
pubmed: 25097069
Mycoses. 2017 Jul;60(7):420-425
pubmed: 28497502
Clin Microbiol Infect. 2012 Dec;18 Suppl 7:19-37
pubmed: 23137135