Adenosine A


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
05 07 2019
Historique:
received: 10 12 2018
accepted: 10 05 2019
entrez: 7 7 2019
pubmed: 7 7 2019
medline: 23 10 2020
Statut: epublish

Résumé

Niemann Pick type C (NPC) disease is a rare neurovisceral disorder. Mutations in npc1 gene induce an intracellular accumulation of unesterified cholesterol in the endosomal/lysosomal system causing cell death. We recently showed that stimulation of adenosine A

Identifiants

pubmed: 31278313
doi: 10.1038/s41598-019-46268-8
pii: 10.1038/s41598-019-46268-8
pmc: PMC6611770
doi:

Substances chimiques

Receptor, Adenosine A2A 0
Cholesterol 97C5T2UQ7J
Cyclic AMP E0399OZS9N
Cyclic AMP-Dependent Protein Kinases EC 2.7.11.11

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9782

Références

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Auteurs

Chiara De Nuccio (C)

Research Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy. chiara.denuccio@iss.it.

Antonietta Bernardo (A)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Antonella Ferrante (A)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Rita Pepponi (R)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Alberto Martire (A)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Mario Falchi (M)

National Research Center on HIV/AIDS, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Sergio Visentin (S)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Patrizia Popoli (P)

National Center for Research and Preclinical and Clinical Evaluation of Drugs, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

Luisa Minghetti (L)

Research Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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Classifications MeSH