Spheroplast-Mediated Carbapenem Tolerance in Gram-Negative Pathogens.
Amdinocillin
/ pharmacology
Anti-Bacterial Agents
/ pharmacology
Drug Tolerance
Enterobacter aerogenes
/ drug effects
Enterobacter cloacae
/ drug effects
Escherichia coli
/ drug effects
Gram-Negative Bacterial Infections
/ drug therapy
Klebsiella pneumoniae
/ drug effects
Meropenem
/ pharmacology
Microbial Sensitivity Tests
Spheroplasts
/ drug effects
L-form
antibiotic
carbapenem
carbapenemase
meropenem
tolerance
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
08
04
2019
accepted:
28
06
2019
pubmed:
10
7
2019
medline:
4
7
2020
entrez:
10
7
2019
Statut:
epublish
Résumé
Antibiotic tolerance, the ability to temporarily sustain viability in the presence of bactericidal antibiotics, constitutes an understudied and yet potentially widespread cause of antibiotic treatment failure. We have previously shown that the Gram-negative pathogen
Identifiants
pubmed: 31285232
pii: AAC.00756-19
doi: 10.1128/AAC.00756-19
pmc: PMC6709500
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Meropenem
FV9J3JU8B1
Amdinocillin
V10579P3QZ
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : R01 AI143704
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM113172
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Microbiology.
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