Mortality in males treated for an eating disorder-A large prospective study.
anorexia nervosa
bulimia nervosa
death
eating disorders
males
standardized mortality ratio
Journal
The International journal of eating disorders
ISSN: 1098-108X
Titre abrégé: Int J Eat Disord
Pays: United States
ID NLM: 8111226
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
13
02
2019
revised:
18
06
2019
accepted:
25
06
2019
pubmed:
11
7
2019
medline:
25
3
2020
entrez:
11
7
2019
Statut:
ppublish
Résumé
To report on the long-term mortality of eating disorders in male inpatients. Crude mortality rates (CMR) and standardized mortality ratios (SMR) were computed for a large sample of males (147 anorexia nervosa [AN], 81 bulimia nervosa [BN], 110 eating disorder not otherwise specified [ED-NOS]; DSM-IV). In addition, a survival analysis from onset of eating disorder to death or end of observation was computed. CMR was 12.9% in AN, 11.1% in BN, and 6.4% in ED-NOS. Standardized mortality was significantly elevated in males with AN (SMR = 5.91; 95% confidence interval 3.56-9.23) as well as ED-NOS (SMR = 3.40; 95% confidence interval 1.37-7.01) but not in males with BN (SMR = 1.88; 95% confidence interval 0.86-3.58). Males with AN died sooner after onset of eating disorder than males with BN or ED-NOS. Mortality in male inpatients with eating disorder is high, especially in AN. There is need for developing more effective treatments to achieve better outcome.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1365-1369Informations de copyright
© 2019 Wiley Periodicals, Inc.
Références
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders: 4th ed. (DSM-IV). Washington, DC: Author.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: 5th ed. (DSM-5). Arlington, VA: Author.
Bland, J. M., & Altman, D. G. (2004). The logrank test. British Medical Journal, 328, 1073. https://doi.org/10.1136/bmj.328.7447.1073
Chan, Y. H. (2004). Biostatistics 203: Survival analysis. Singapore Medical Journal, 45(6), 249-256.
Crisp, A., & Collaborators. (2006). Anorexia nervosa in males: Similarities and differences to anorexia nervosa in females. European Eating Disorders Review, 14, 163-167. https://doi.org/10.1002/erv.703
Federal Office of Statistics, Mortality figures. https://www.destatis.de/DE/Publikationen/Thematisch/Bevoelkerung/Bevoelkerungsbewegung/PeriodensterbetafelnPDF_5126202.pdf?__blob=publicationFile.
Fichter, M. M., & Quadflieg, N. (2000). Comparing self- and expert rating: A self-report screening version (SIAB-S) of the structured interview for anorexic and bulimic syndromes for DSM-IV and ICD-10 (SIAB-EX). European Archives of Psychiatry and Clinical Neuroscience, 250, 175-185. https://doi.org/10.1007/s004060070022
Fichter, M. M., & Quadflieg, N. (2016). Mortality in eating disorders-Results of a large prospective clinical longitudinal study. International Journal of Eating Disorders, 49, 391-401. https://doi.org/10.1002/eat.22501
Fichter, M. M., Quadflieg, N., Crosby, R. D., & Koch, S. (2017). Long-term outcome of anorexia nervosa: Results from a large clinical longitudinal study. International Journal of Eating Disorders, 50, 1018-1030. https://doi.org/10.1002/eat.22736
Griffiths, S., Mond, J. M., Li, Z., Gunatilake, S., Murray, S. B., Sheffield, J., & Touyz, S. (2015). Self-stigma of seeking treatment and being male predict an increased likelihood of having an undiagnosed eating disorder. International Journal of Eating Disorders, 48, 775-778. https://doi.org/10.1002/eat.22413
Gueguen, J., Godart, N., Chambry, J., Brun-Eberentz, A., Foulon, C., Divac, S. M., … Huas, C. (2012). Severe anorexia nervosa in men: Comparison with severe AN in women and analysis of mortality. International Journal of Eating Disorders, 45, 537-545. https://doi.org/10.1002/eat.20987
Hoang, U., Goldacre, M., & James, A. (2014). Mortality following hospital discharge with a diagnosis of eating disorder: National Record Linkage Study, England, 2001-2009. International Journal of Eating Disorders, 47(5), 507-515. https://doi.org/10.1002/eat.22249
Kask, J., Ramklint, M., Kolia, N., Panagiotakos, D., Ekbom, A., Ekselius, L., & Papadopoulos, F. C. (2017). Anorexia nervosa in males: Excess mortality and psychiatric co-morbidity in 609 Swedish in-patients. Psychological Medicine, 47, 1489-1499. https://doi.org/10.1111/j.2044-8341.1986.tb02676.x
Keel, P. K., Dorer, D. J., Eddy, K. T., Franko, D., Charatan, D. L., & Herzog, D. B. (2003). Predictors of mortality in eating disorders. Archives of General Psychiatry, 60, 179-183. https://doi.org/10.1001/archpsyc.60.2.179
Keshaviaha, A., Edkinsa, K., Hastings, E. R., Krishnaa, M., Franko, D. L., Herzog, D. B., … Eddy, K. T. (2014). Re-examining premature mortality inanorexia nervosa: A meta-analysis redux. Comprehensive Psychiatry, 55, 1773-1784. https://doi.org/10.1016/j.comppsych.2014.07.017
Korndörfer, S. R., Lucas, A. R., Suman, V. J., Crowson, C. S., Krahn, L. E., & Melton III, L. J. (2003). Long-term survival of patients with anorexia nervosa: Apopulation-based study in Rochester, Minn. Mayo Clinic Proceedings, 78, 278-284. https://doi.org/10.4065/78.3.278
Møller-Madsen, S., Nystrup, J., & Nielsen, S. (1996). Mortality in anorexia nervosa in Denmark during the period 1970-1987. Acta Psychiatrica Scandinavica, 94, 454-459. https://doi.org/10.1111/j.1600-0447.1996.tb09890.x
Quadflieg, N., & Fichter, M. M. (in press). Long-term outcome of inpatients with bulimia nervosa-Results from the Christina Barz Study. International Journal of Eating Disorders. https://doi.org/10.1002/eat.23084
Strobel, C., Quadflieg, N., Naab, S., Voderholzer, U., & Fichter, M. M. (under review). Long-term outcomes in treated males with anorexia nervosa and bulimia nervosa-A prospective, controlled study. International Journal of Eating Disorders.
Strobel, C., Quadflieg, N., Voderholzer, U., Naab, S., & Fichter, M. M. (2018). Short- and long-term outcome of males treated for anorexia nervosa: A review of the literature. Eating and Weight Disorders, 23, 541-552. https://doi.org/10.1007/s40519-018-0538-6
Taeger, D., Sun, Y., Keil, U., & Straif, K. (2000). A stand-alone Windows application for computing exact person-years, standardized mortality ratios and confidence intervals in epidemiological studies. Epidemiology, 11, 607-608. https://doi.org/10.1097/00001648-200009000-00019