Comparison of Glycated Ovalbumin-Monosaccharides in the Attenuation of Ovalbumin-Induced Allergic Response in a BALB/C Mouse Model.
MHC class II
dendritic cells
glycation
mannose receptor
ovalbumin
Journal
Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755
Informations de publication
Date de publication:
24 Jul 2019
24 Jul 2019
Historique:
pubmed:
12
7
2019
medline:
10
8
2019
entrez:
12
7
2019
Statut:
ppublish
Résumé
The aim of the present study was to compare various glycated ovalbumin (OVA)-monosaccharides, including OVA-mannose (Man), -glucose, -ribose, and -fructose, in the attenuation of OVA-induced allergic response in a BALB/C mouse model and the potential mechanisms of immunological modulation. The glycated OVA forms were prepared by Maillard reactions. OVA-Man significantly reduced the frequency of allergic signs. Mouse mast cell protease enzyme concentration was significantly reduced in the OVA-Man group (549.80 ± 84.67 ng/mL,
Identifiants
pubmed: 31294563
doi: 10.1021/acs.jafc.9b02132
doi:
Substances chimiques
Cytokines
0
Monosaccharides
0
Immunoglobulin E
37341-29-0
Ovalbumin
9006-59-1
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM