Bioactivity and Mode of Action of Bacterial Tetramic Acids.

Anti-Bacterial Agents / chemical synthesis Methicillin-Resistant Staphylococcus aureus / drug effects Microbial Sensitivity Tests Molecular Structure Mycobacteriaceae / drug effects Pyrrolidinones / chemical synthesis Structure-Activity Relationship

Journal

ACS chemical biology
ISSN: 1554-8937
Titre abrégé: ACS Chem Biol
Pays: United States
ID NLM: 101282906

Informations de publication

Date de publication:
16 08 2019
Historique:
pubmed: 12 7 2019
medline: 4 1 2020
entrez: 12 7 2019
Statut: ppublish

Résumé

Microbially produced 3-acyltetramic acids display a diverse range of biological activities. The pyreudiones are new members of this class that were isolated from bacteria of the genus

Identifiants

DOI: 10.1021/acschembio.9b00388 PMID: 31294961
pubmed: 31294961
doi: 10.1021/acschembio.9b00388
doi:

Substances chimiques

Anti-Bacterial Agents 0
Pyrrolidinones 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1693-1697

Auteurs

Martin Klapper (M)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

André Paschold (A)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Shuaibing Zhang (S)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Christiane Weigel (C)

Department of Molecular and Applied Microbiology , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Hans-Martin Dahse (HM)

Department of Infection Biology , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Sebastian Götze (S)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Simona Pace (S)

Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy , Friedrich-Schiller-University Jena , Philosophenweg 14 , 07743 , Jena , Germany.

Stefanie König (S)

Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy , Friedrich-Schiller-University Jena , Philosophenweg 14 , 07743 , Jena , Germany.

Zhigang Rao (Z)

Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy , Friedrich-Schiller-University Jena , Philosophenweg 14 , 07743 , Jena , Germany.

Lisa Reimer (L)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.

Oliver Werz (O)

Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy , Friedrich-Schiller-University Jena , Philosophenweg 14 , 07743 , Jena , Germany.

Pierre Stallforth (P)

Independent Junior Research Group Chemistry of Microbial Communication , Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI) , Beutenbergstrasse 11a , 07745 Jena , Germany.
ORCID: 0000-0001-7260-9921

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrrolidines › Pyrrolidones › Bioactivity and Mode of Action of Bacterial...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Bioactivity and Mode of Action of Bacterial...