Sudden cardiac death: an update.

cardiomyopathy implantable cardiac defibrillator ischaemic heart disease primary arrhythmia syndrome sudden cardiac death sudden unexplained death

Journal

Internal medicine journal
ISSN: 1445-5994
Titre abrégé: Intern Med J
Pays: Australia
ID NLM: 101092952

Informations de publication

Date de publication:
07 2019
Historique:
received: 23 03 2019
revised: 11 04 2019
accepted: 16 04 2019
entrez: 12 7 2019
pubmed: 12 7 2019
medline: 15 2 2020
Statut: ppublish

Résumé

Sudden cardiac death (SCD) is a devastating and all too common result of both acquired and genetic heart diseases. The profound sadness endured by families is compounded by the risk many of these deaths confer upon surviving relatives. For those with known cardiac disease, disease-specific therapy and risk stratification are key to reducing sudden death. For families of a SCD victim, uncovering a definitive cause of death can help relieve the agonising uncertainty and is a vital first step in screening surviving relatives and instituting therapy to reduce SCD risk. Increasing knowledge about the molecular mechanisms and genetic drivers of malignant arrhythmias in the diverse clinical entities that can cause SCD is vital if we are to optimise risk stratification and personalise patient care. Advances in diagnostic tools, disease-specific therapy and defibrillator technology are improving outcomes for patients and their families but there is still much progress to be made.

Identifiants

pubmed: 31295785
doi: 10.1111/imj.14359
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

826-833

Subventions

Organisme : National Health and Medical Research Council Practitioner Fellowship
ID : 1154992
Pays : International
Organisme : Cardiac Society of Australia and New Zealand Research Scholarship
Pays : International

Informations de copyright

© 2019 Royal Australasian College of Physicians.

Auteurs

Julia Isbister (J)

Agnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.
Faculty of Medicine and Heath, The University of Sydney, Sydney, New South Wales, Australia.

Christopher Semsarian (C)

Agnes Ginges Centre for Molecular Cardiology at Centenary Institute, The University of Sydney, Sydney, New South Wales, Australia.
Faculty of Medicine and Heath, The University of Sydney, Sydney, New South Wales, Australia.
Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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Classifications MeSH