Self-harm in women with postpartum mental disorders.


Journal

Psychological medicine
ISSN: 1469-8978
Titre abrégé: Psychol Med
Pays: England
ID NLM: 1254142

Informations de publication

Date de publication:
07 2020
Historique:
pubmed: 13 7 2019
medline: 14 5 2021
entrez: 13 7 2019
Statut: ppublish

Résumé

Women suffering from first onset postpartum mental disorders (PPMD) have a highly elevated risk of suicide. The current study aimed to: (1) describe the risk of self-harm among women with PPMD and (2) investigate the extent to which self-harm is associated with later suicide. We conducted a register-based cohort study linking national Danish registers. This identified women with any recorded first inpatient or outpatient contact to a psychiatric facility within 90 days after giving birth to their first child. The main outcome of interest was defined as the first hospital-registered episode of self-harm. Our cohort consisted of 1 202 292 women representing 24 053 543 person-years at risk. Among 1554 women with severe first onset PPMD, 64 had a first-ever hospital record of self-harm. Women with PPMD had a hazard ratio (HR) for self-harm of 6.2 (95% CI 4.9-8.0), compared to mothers without mental disorders; but self-harm risk was lower in PPMD women compared to mothers with non-PPMD [HR: 10.1, (95% CI 9.6-10.5)] and childless women with mental disorders [HR: 9.3 (95% CI 8.9-9.7)]. Women with PPMD and records of self-harm had a significantly greater risk for later suicide compared with all other groups of women in the cohort. Women with PPMD had a high risk of self-harm, although lower than risks observed in other psychiatric patients. However, PPMD women who had self-harmed constituted a vulnerable group at significantly increased risk of later suicide.

Sections du résumé

BACKGROUND
Women suffering from first onset postpartum mental disorders (PPMD) have a highly elevated risk of suicide. The current study aimed to: (1) describe the risk of self-harm among women with PPMD and (2) investigate the extent to which self-harm is associated with later suicide.
METHODS
We conducted a register-based cohort study linking national Danish registers. This identified women with any recorded first inpatient or outpatient contact to a psychiatric facility within 90 days after giving birth to their first child. The main outcome of interest was defined as the first hospital-registered episode of self-harm. Our cohort consisted of 1 202 292 women representing 24 053 543 person-years at risk.
RESULTS
Among 1554 women with severe first onset PPMD, 64 had a first-ever hospital record of self-harm. Women with PPMD had a hazard ratio (HR) for self-harm of 6.2 (95% CI 4.9-8.0), compared to mothers without mental disorders; but self-harm risk was lower in PPMD women compared to mothers with non-PPMD [HR: 10.1, (95% CI 9.6-10.5)] and childless women with mental disorders [HR: 9.3 (95% CI 8.9-9.7)]. Women with PPMD and records of self-harm had a significantly greater risk for later suicide compared with all other groups of women in the cohort.
CONCLUSIONS
Women with PPMD had a high risk of self-harm, although lower than risks observed in other psychiatric patients. However, PPMD women who had self-harmed constituted a vulnerable group at significantly increased risk of later suicide.

Identifiants

pubmed: 31298172
pii: S0033291719001661
doi: 10.1017/S0033291719001661
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1563-1569

Subventions

Organisme : Department of Health
ID : DRF-2016-09-042
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R01 MH104468
Pays : United States

Auteurs

Benedicte Marie Johannsen (BM)

National Center for Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.

Janne Tidselbak Larsen (JT)

National Center for Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.
CIRRAU, Centre for Integrated Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.

Thomas Munk Laursen (TM)

National Center for Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.
CIRRAU, Centre for Integrated Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.

Karyn Ayre (K)

Section of Women's Mental Health, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Louise M Howard (LM)

Section of Women's Mental Health, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Samantha Meltzer-Brody (S)

Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, USA.

Bodil Hammer Bech (BH)

Department of Public Health, Research Unit of Epidemiology, Aarhus University, Aarhus, Denmark.

Trine Munk-Olsen (T)

National Center for Register-based Research, Aarhus University, Fuglesangs Allé 26, 8210Aarhus, Denmark.

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