Symptoms, disease severity and treatment of adults with a new diagnosis of severe aortic stenosis.
Age Factors
Aged
Aged, 80 and over
Aortic Valve
/ diagnostic imaging
Aortic Valve Stenosis
/ diagnostic imaging
Asymptomatic Diseases
Comorbidity
Cross-Sectional Studies
Echocardiography
Europe
Female
Hemodynamics
Humans
Male
Predictive Value of Tests
Prognosis
Prospective Studies
Registries
Risk Assessment
Risk Factors
Severity of Illness Index
Ventricular Function, Left
aortic stenosis
surgical aortic valve replacement
symptoms
transcatheter aortic valve replacement
Journal
Heart (British Cardiac Society)
ISSN: 1468-201X
Titre abrégé: Heart
Pays: England
ID NLM: 9602087
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
02
05
2019
revised:
18
06
2019
accepted:
21
06
2019
pubmed:
16
7
2019
medline:
17
6
2020
entrez:
15
7
2019
Statut:
ppublish
Résumé
Contemporary data on patients with previously undiagnosed severe aortic stenosis (AS) are scarce. We aimed to address this gap by gathering data from consecutive patients diagnosed with severe AS on echocardiography. This was a prospective, multicentre, multinational, registry in 23 tertiary care hospitals across 9 European countries. Patients with a diagnosis of severe AS were included using echocardiography (aortic valve area (AVA) <1 cm The 2171 participants had a mean age of 77.9 years and 48.0% were female. The mean AVA was 0.73 cm The majority of patients with severe AS presented at an advanced disease stage. Management of severe AS remained suboptimal in a significant proportion of contemporary patients with severe AS. NCT02241447;Results.
Identifiants
pubmed: 31302639
pii: heartjnl-2019-314940
doi: 10.1136/heartjnl-2019-314940
doi:
Banques de données
ClinicalTrials.gov
['NCT02241447']
Types de publication
Comparative Study
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1709-1716Commentaires et corrections
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: PB is the representative of the IPPMed. NF, RPS, TKR and DM-Z have received speakers’ honoraria from Edwards Lifesciences. The institutions of these three and those of the remaining authors representing study centers have received funding from the sponsor for employing a study nurse for the duration of the study. IPPMed designed and executed the study, collected and analysed the data and drafted/revised the manuscript in collaboration with the other authors.