Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner.
Carrier Proteins
/ chemistry
Drug Repositioning
Enterovirus B, Human
/ drug effects
Enterovirus D, Human
/ drug effects
Fluoxetine
/ pharmacology
HeLa Cells
Humans
Models, Molecular
Molecular Structure
Mutation
Protein Binding
Protein Conformation
Structural Homology, Protein
Viral Nonstructural Proteins
/ chemistry
Virus Replication
/ drug effects
antiviral
drug repurposing
enteroviruses
molecular modeling
virus replication
Journal
ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580
Informations de publication
Date de publication:
13 09 2019
13 09 2019
Historique:
pubmed:
16
7
2019
medline:
18
6
2020
entrez:
16
7
2019
Statut:
ppublish
Résumé
Enteroviruses (family
Identifiants
pubmed: 31305993
doi: 10.1021/acsinfecdis.9b00179
pmc: PMC6747591
doi:
Substances chimiques
Carrier Proteins
0
Viral Nonstructural Proteins
0
Fluoxetine
01K63SUP8D
2C protein, viral
EC 3.6.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1609-1623Références
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