Vitamin D differentially regulates colon stem cells in patient-derived normal and tumor organoids.
colon cancer
colon stem cells
organoids
stemness genes
vitamin D
Journal
The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
19
06
2019
accepted:
12
07
2019
pubmed:
16
7
2019
medline:
9
7
2020
entrez:
16
7
2019
Statut:
ppublish
Résumé
Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, the putative effects of 1α,25-dihydroxyvitamin D
Identifiants
pubmed: 31306552
doi: 10.1111/febs.14998
pmc: PMC6972655
doi:
Substances chimiques
Calcium Channel Agonists
0
Receptors, Calcitriol
0
VDR protein, human
0
Calcitriol
FXC9231JVH
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
53-72Informations de copyright
© 2019 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
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