The effect of less invasive surfactant administration on cerebral oxygenation in preterm infants.


Journal

Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968

Informations de publication

Date de publication:
02 2020
Historique:
received: 19 10 2018
revised: 13 06 2019
accepted: 11 07 2019
pubmed: 17 7 2019
medline: 15 5 2021
entrez: 17 7 2019
Statut: ppublish

Résumé

To determine the regional cerebral tissue oxygenation saturation (rcSO In preterm infants with a gestational age 26 0/7-31 6/7 weeks, we conducted an observational study using near-infrared spectroscopy (NIRS) in the first 120 hours of life. We analysed the data of 22 infants who never received surfactant (CPAP), 22 infants had LISA and CPAP (LISA) and 6 infants received surfactant via endotracheal tube (ETT). Four infants had both surfactant application modes including six LISA applications. In total, there were 32 successful LISA applications but 44 attempts; 13/44 (30%) of LISA attempts resulted in a 20% decrease of rcSO Our observational data indicate that rcSO

Identifiants

pubmed: 31310677
doi: 10.1111/apa.14939
doi:

Substances chimiques

Pulmonary Surfactants 0
Surface-Active Agents 0

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

291-299

Informations de copyright

©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Références

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Auteurs

Kathrin Hanke (K)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Tanja K Rausch (TK)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.
Institute for Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany.

Pia Paul (P)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Isabel Hellwig (I)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Christina Krämer (C)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Guido Stichtenoth (G)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Alexander Herz (A)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Christian Wieg (C)

Department of Neonatology, Klinikum Aschaffenburg-Alzenau, Aschaffenburg, Germany.

Inke R König (IR)

Institute for Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany.

Wolfgang Göpel (W)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Egbert Herting (E)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

Christoph Härtel (C)

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

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