Integrated biomarker response index to assess toxic effects of environmentally relevant concentrations of paracetamol in a neotropical catfish (Rhamdia quelen).

Acetaminophen / toxicity Animals Anti-Inflammatory Agents, Non-Steroidal Biomarkers / metabolism Catalase Catfishes / physiology DNA Damage Gills / drug effects Glutathione / pharmacology Glutathione Peroxidase Glutathione Transferase Water Pollutants, Chemical / toxicity
DNA damage NSAIDs Nephrotoxicity Oxidative stress Paracetamol Rhamdia quelen

Journal

Ecotoxicology and environmental safety
ISSN: 1090-2414
Titre abrégé: Ecotoxicol Environ Saf
Pays: Netherlands
ID NLM: 7805381

Informations de publication

Date de publication:
30 Oct 2019
Historique:
received: 25 01 2019
revised: 01 07 2019
accepted: 09 07 2019
pubmed: 17 7 2019
medline: 23 10 2019
entrez: 17 7 2019
Statut: ppublish

Résumé

The nonsteroidal anti-inflammatory drugs (NSAIDs) are amongst the most commonly detected classes of pharmaceuticals in freshwater environments, with paracetamol being the most abundant. The aim of this study was to evaluate the possible toxic effects of environmentally relevant concentrations (0.25, 2.5 and 25 μg.L

Identifiants

DOI: 10.1016/j.ecoenv.2019.109438 PMID: 31310901
pubmed: 31310901
pii: S0147-6513(19)30769-9
doi: 10.1016/j.ecoenv.2019.109438
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents, Non-Steroidal 0
Biomarkers 0
Water Pollutants, Chemical 0
Acetaminophen 362O9ITL9D
Catalase EC 1.11.1.6
Glutathione Peroxidase EC 1.11.1.9
Glutathione Transferase EC 2.5.1.18
Glutathione GAN16C9B8O

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109438

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Maiara C Perussolo (MC)

Department of Pharmacology, Federal University of Paraná (UFPR), Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: maiaraperussolo@ufpr.br.

Izonete Cristina Guiloski (IC)

Department of Pharmacology, Federal University of Paraná (UFPR), Box 19031, 81530-980, Curitiba, PR, Brazil; Department of Genetics, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: iguiloski@gmail.com.

Juliana Roratto Lirola (JR)

Department of Genetics, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: julianaroratto91@hotmail.com.

Douglas Henrique Fockink (DH)

Department of Chemistry, Federal University of Paraná (UFPR), P.O. Box 19032, 81531-980, Curitiba, PR, Brazil. Electronic address: douglasfockink@ufpr.br.

Claudia Rita Corso (CR)

Department of Pharmacology, Federal University of Paraná (UFPR), Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: claudia_rcorso@hotmail.com.

Deivyson Cattine Bozza (DC)

Department of Physiology, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: deivysonbozza@gmail.com.

Viviane Prodocimo (V)

Department of Physiology, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: vprodocimo@ufpr.br.

Maritana Mela (M)

Department of Cell Biology, Federal University of Paraná, P.O. Box 19031, 81530- 980, Curitiba, PR, Brazil. Electronic address: maritana.mela@ufpr.br.

Luiz Pereira Ramos (LP)

Department of Chemistry, Federal University of Paraná (UFPR), P.O. Box 19032, 81531-980, Curitiba, PR, Brazil. Electronic address: luiz.ramos@ufpr.br.

Marta Margarete Cestari (MM)

Department of Genetics, Federal University of Paraná, P.O. Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: margaces@ufpr.br.

Alexandra Acco (A)

Department of Pharmacology, Federal University of Paraná (UFPR), Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: aleacco@ufpr.br.

Helena Cristina Silva de Assis (HC)

Department of Pharmacology, Federal University of Paraná (UFPR), Box 19031, 81530-980, Curitiba, PR, Brazil. Electronic address: helassis@ufpr.br.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Anilides › Acétanilides › Acétaminophène › Integrated biomarker response index to assess...
questionsmedicales.fr › Eucaryotes › Animaux › Integrated biomarker response index to assess...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antirhumatismaux › Anti-inflammatoires non stéroïdiens › Integrated biomarker response index to assess...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Integrated biomarker response index to assess...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Peroxidases › Catalase › Integrated biomarker response index to assess...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Poissons-chats › Integrated biomarker response index to assess...
questionsmedicales.fr › Phénomènes génétiques › Altération de l'ADN › Integrated biomarker response index to assess...
questionsmedicales.fr › Structures anatomiques de l'animal › Branchies › Integrated biomarker response index to assess...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › Glutathion › Integrated biomarker response index to assess...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Sélénoprotéines › Glutathione peroxidase › Integrated biomarker response index to assess...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Alkyl et aryl transferases › Glutathione transferase › Integrated biomarker response index to assess...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants de l'eau › Polluants chimiques de l'eau › Integrated biomarker response index to assess...