Changes in bone mineral density and bone metabolism after sleeve gastrectomy: a systematic review and meta-analysis.
Bone
Calcium
Meta-analysis
Obesity
Sleeve gastrectomy
Journal
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
ISSN: 1878-7533
Titre abrégé: Surg Obes Relat Dis
Pays: United States
ID NLM: 101233161
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
31
03
2019
revised:
11
05
2019
accepted:
10
06
2019
pubmed:
18
7
2019
medline:
28
7
2020
entrez:
18
7
2019
Statut:
ppublish
Résumé
Roux-en-Y gastric bypass surgery adversely affects bone health. The evidence is less well-described for sleeve gastrectomy (SG). To better characterize bone metabolism changes after SG. Systematic review and meta-analysis. MEDLINE and EMBASE were searched through March 2019 for eligible studies assessing adults with obesity aged 18 years or older that underwent SG. Bone mineral density (BMD), serum calcium, serum phosphate, serum 25-hydroxyvitamin D, serum parathyroid hormone, or serum alkaline phosphatase were reported at baseline and after SG; and a follow-up duration was at least 6 months. Preoperative and postoperative mean of each outcome of interest and corresponding standard deviations were extracted from each study and the mean difference (MD) was calculated. Pooled MD was then calculated by combining MDs of each study using random-effects model. A total of 22 studies with 1905 patients with obesity that underwent SG were included. There were significant decreases in total hip BMD (pooled MD of -.06 g/cm The present study found a decreased BMD among patients with obesity after SG.
Sections du résumé
BACKGROUND
BACKGROUND
Roux-en-Y gastric bypass surgery adversely affects bone health. The evidence is less well-described for sleeve gastrectomy (SG).
OBJECTIVES
OBJECTIVE
To better characterize bone metabolism changes after SG.
SETTING
METHODS
Systematic review and meta-analysis.
METHODS
METHODS
MEDLINE and EMBASE were searched through March 2019 for eligible studies assessing adults with obesity aged 18 years or older that underwent SG. Bone mineral density (BMD), serum calcium, serum phosphate, serum 25-hydroxyvitamin D, serum parathyroid hormone, or serum alkaline phosphatase were reported at baseline and after SG; and a follow-up duration was at least 6 months. Preoperative and postoperative mean of each outcome of interest and corresponding standard deviations were extracted from each study and the mean difference (MD) was calculated. Pooled MD was then calculated by combining MDs of each study using random-effects model.
RESULTS
RESULTS
A total of 22 studies with 1905 patients with obesity that underwent SG were included. There were significant decreases in total hip BMD (pooled MD of -.06 g/cm
CONCLUSIONS
CONCLUSIONS
The present study found a decreased BMD among patients with obesity after SG.
Identifiants
pubmed: 31311755
pii: S1550-7289(19)30279-5
doi: 10.1016/j.soard.2019.06.006
pii:
doi:
Substances chimiques
Parathyroid Hormone
0
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1252-1260Informations de copyright
Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.