Platelet to lymphocyte ratio as a predictive factor of 30-day mortality in patients with acute mesenteric ischemia.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 30 04 2019
accepted: 02 07 2019
entrez: 18 7 2019
pubmed: 18 7 2019
medline: 10 3 2020
Statut: epublish

Résumé

Acute mesenteric ischemia is associated with high rates of mortality. The aim of this study was to investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) on 30-day outcomes in patients with acute mesenteric ischemia. Consecutive patients who were admitted for an acute mesenteric ischemia were retrospectively included. The full white blood count at the time of admission to the hospital was recorded. The population was divided into 4 subgroups according to the quartiles of the NLR and the PLR. The 30-day outcomes including the mortality and the complications were compared among the subgroups. In total, 106 patients were included. A surgical treatment including revascularization and/or digestive resection was performed for 56 patients (52.8%). The 30-day all-cause mortality was 72 patients (67.9%). Patients with higher PLR value (PLR >429.3) had significantly higher rate of mortality compared to the other groups (80.8% vs 46.2%, 66.7% and 77.8%, p = 0.03). No significant difference on 30-day outcome was observed among the subgroups divided according to the NLR. The PLR, but not the NLR, is a predictive factor of 30-day mortality in patients with acute mesenteric ischemia.

Identifiants

pubmed: 31314768
doi: 10.1371/journal.pone.0219763
pii: PONE-D-19-12218
pmc: PMC6636734
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0219763

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Emmanuel Augène (E)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.

Fabien Lareyre (F)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.
Université Côte d'Azur, CHU, Nice, France.

Julien Chikande (J)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.

Lucas Guidi (L)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.

Ali Ballaith (A)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.

Jean-Nicolas Bossert (JN)

Unit of Vascular Surgery, CHU de Bordeaux, University of Bordeaux, Bordeaux, France.

Yann Pelletier (Y)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.

Caroline Caradu (C)

Unit of Vascular Surgery, CHU de Bordeaux, University of Bordeaux, Bordeaux, France.

Réda Hassen-Khodja (R)

Department of Vascular Surgery, University Hospital of Nice, Nice, France.
Université Côte d'Azur, CHU, Nice, France.

Juliette Raffort (J)

Université Côte d'Azur, CHU, Nice, France.
Clinical Chemistry Laboratory, University Hospital of Nice, Nice, France.

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