The Prognosis of Stage IA Mixed Endometrial Carcinoma.

Adenocarcinoma, Clear Cell / mortality Adult Carcinoma, Endometrioid / mortality Chemoradiotherapy, Adjuvant Cohort Studies Cystadenocarcinoma, Serous / mortality Disease-Free Survival Endometrial Neoplasms / mortality Female Humans Middle Aged Neoplasm Staging Prognosis Retrospective Studies Survival Rate
Disease-free survival Mixed endometrial carcinoma Overall survival

Journal

American journal of clinical pathology
ISSN: 1943-7722
Titre abrégé: Am J Clin Pathol
Pays: England
ID NLM: 0370470

Informations de publication

Date de publication:
07 10 2019
Historique:
pubmed: 19 7 2019
medline: 26 3 2020
entrez: 19 7 2019
Statut: ppublish

Résumé

To explore the survival and definition of stage IA mixed endometrial carcinoma. From June 1, 2010, to June 1, 2017, cases with stage IA endometrial cancer were included in this study. The survival outcomes were compared among patients with endometrioid (group A), nonendometrioid (group B), and mixed subtypes (group C) and among patients with different proportions of nonendometrioid components (<5%, >50%, and others). In total, 890 cases were included, comprising 808 (90.8%), 33 (3.7%), and 47 (5.3%) cases in groups A, B, and C, respectively. After a median follow-up of 55.9 months, groups B and C had significantly more inferior disease-free survival, overall survival, and cancer-specific overall survival. Patients with a nonendometrioid proportion of more than 50% and serous subtype also had a significantly more inferior prognosis. Adjuvant therapy could improve the prognosis in mixed endometrial carcinomas. Patients with endometrial cancer of mixed subtypes had inferior survival outcomes.

Identifiants

DOI: 10.1093/ajcp/aqz083 PMID: 31318970
pubmed: 31318970
pii: 5535754
doi: 10.1093/ajcp/aqz083
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

616-624

Informations de copyright

© American Society for Clinical Pathology, 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Wenhui Li (W)

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.

Lei Li (L)

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.

Ming Wu (M)

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.

Jinghe Lang (J)

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.

Yalan Bi (Y)

Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.

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Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Adénocarcinome à cellules claires › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Maladies ovariennes › Tumeurs de l'ovaire › Carcinome endométrioïde › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Thérapeutique › Radiothérapie › Chimioradiothérapie › Chimioradiothérapie adjuvante › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Tumeurs kystiques, mucineuses et séreuses › Cystadénocarcinome › Cystadénocarcinome séreux › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Survie sans rechute › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital féminin › Tumeurs de l'utérus › Tumeurs de l'endomètre › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Diagnostic › Pronostic › Stadification tumorale › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Diagnostic › Pronostic › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › The Prognosis of Stage IA Mixed Endometrial Carcinoma.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Mortalité › Taux de survie › The Prognosis of Stage IA Mixed Endometrial Carcinoma.