12th GCC Closed Forum: critical reagents; oligonucleotides; CoA; method transfer; HRMS; flow cytometry; regulatory findings; stability and immunogenicity.

CRO GCC HRMS certificate of analysis critical reagents flow cytometry method transfer oligonucleotides regulatory findings stability and immunogenicity

Journal

Bioanalysis
ISSN: 1757-6199
Titre abrégé: Bioanalysis
Pays: England
ID NLM: 101512484

Informations de publication

Date de publication:
Jun 2019
Historique:
pubmed: 20 7 2019
medline: 18 12 2019
entrez: 20 7 2019
Statut: ppublish

Résumé

The 12th GCC Closed Forum was held in Philadelphia, PA, USA, on 9 April 2018. Representatives from international bioanalytical Contract Research Organizations were in attendance in order to discuss scientific and regulatory issues specific to bioanalysis. The issues discussed at the meeting included: critical reagents; oligonucleotides; certificates of analysis; method transfer; high resolution mass spectrometry; flow cytometry; recent regulatory findings and case studies involving stability and nonclinical immunogenicity. Conclusions and consensus from discussions of these topics are included in this article.

Identifiants

pubmed: 31319683
doi: 10.4155/bio-2019-0131
doi:

Substances chimiques

Indicators and Reagents 0
Oligonucleotides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1129-1138

Auteurs

Chad Briscoe (C)

PRA Health Sciences, Lenexa, KS, USA.

Nicola Hughes (N)

BioPharma Services, 4000 Weston Road, North York, Toronto, M9L 3A2 Ontario, Canada.

Roger Hayes (R)

MPI Research, Mattawan, MI 49071, USA.

Rafiq Islam (R)

Celerion, Lincoln, Nebraska, NE 68502, USA.

Patrick Bennett (P)

PPD Laboratories, Richmond, VA 23230, USA.

Bruce Stouffer (B)

PPD Laboratories, Richmond, VA 23230, USA.

Stephanie Cape (S)

Covance, Madison, WI 53704, USA.

Paul Rhyne (P)

Immunologix Laboratories, Tampa, FL 33634, USA.

Chris Beaver (C)

Syneos Health, Princeton, NJ 08540, USA.

Jessica St Charles (JS)

MPI Research, Mattawan, MI 49071, USA.

Vellalore Kakkanaiah (V)

PPD Laboratories, Richmond, VA 23230, USA.

Allan Xu (A)

Keystone Bioanalytical, North wales, PA 19454, USA.

Maria Cruz Caturla (MC)

Anapharm Bioanalytics, Barcelona 08038, Spain.

Franklin Spriggs (F)

KCAS Bioanalytical & Biomarker Services, Shawnee Mission, KS 66216, USA.

Rabab Tayyem (R)

ACDIMA Center for Bioequivalence & Pharmaceutical Studies, Amman, Jordan.

Colin Barry (C)

Alliance Pharma, Malvern, PA 19355, USA.

Anahita Keyhani (A)

Altasciences, Laval, Quebec H7V 4B3, Canada.

Jennifer Zimmer (J)

Alturas Analytics, Moscow, ID 83843, USA.

Philippe Couerbe (P)

Atlanbio, Route de Saint-André des Eaux, Saint-Nazaire 44600, France.

Mark Warren (M)

Atlanbio, Route de Saint-André des Eaux, Saint-Nazaire 44600, France.

Ardeshir Khadang (A)

Axis Clinicals, Dilworth, MN 56529, USA.

James Bourdage (J)

BASi, West Lafayette, IN 47906, USA.

Kathie Lindley (K)

BioAgilytix, Durham, NC 27713, USA.

Dave Williams (D)

BioAgilytix, Durham, NC 27713, USA.

Curtis Sheldon (C)

Celerion, Lincoln, Nebraska, NE 68502, USA.

Christina Satterwhite (C)

Charles River Laboratories, Reno, NV 89511, USA.

Jenifer Vija (J)

Charles River Laboratories, Skokie, IL 60077, USA.

Mathilde Yu (M)

CIRION Biopharma Research, Laval, Quebec H7L 5E1, Canada.

Iohann Boulay (I)

CiToxLAB North America, Laval, Quebec H7V 4B3, Canada.

John Stamatopoulos (J)

CiToxLAB North America, Laval, Quebec H7V 4B3, Canada.

Jenny Lin (J)

CMIC, Hoffman Estates, IL 60192, USA.

Sian Estdale (S)

Covance, Harrogate, HG3 1PY, UK.

Eric Thomas (E)

Covance, Indianapolis, IN 46214, USA.

Andrew Dinan (A)

CPR Pharma Services, Adelaide, SA 5031, Australia.

Robert MacNeill (R)

Envigo, Somerset, NJ 08873, USA.

Yi Qun Xiao (YQ)

Envigo, Somerset, NJ 08873, USA.

Luca Matassa (L)

Frontage Lab, Exton, PA 19341, USA.

Wei Garofolo (W)

Grand Challenges Canada, Toronto, Ontario M5G 1M1, Canada.

Natasha Savoie (N)

Grand Challenges Canada, Toronto, Ontario M5G 1M1, Canada.

George Hristopoulos (G)

Intertek, San Diego, CA 92121, USA.

Arron Xu (A)

Intertek, San Diego, CA 92121, USA.

Lawrence Goodwin (L)

KCAS Bioanalytical & Biomarker Services, Shawnee Mission, KS 66216, USA.

Kayode Awaiye (K)

Lambda Therapeutic Research, Toronto, Ontario M1L 4S4, Canada.

Hanna Ritzén (H)

Mercodia AB, Uppsala 754 50, Sweden.

Mohammed Bouhajib (M)

Pharma Medica Research Inc., Mississauga, Ontario L5R 0B7, Canada.

Chantal Di Marco (CD)

Pharma Medica Research Inc., Mississauga, Ontario L5R 0B7, Canada.

Simona Rizea Savu (SR)

Pharma Serv International, Bucharest 050853, Romania.

Corey Nehls (C)

PPD Laboratories, Richmond, VA 23230, USA.

Edward Tabler (E)

PPD Laboratories, Richmond, VA 23230, USA.

Amanda Hays (A)

PRA Health Sciences, Lenexa, KS, USA.

Shane Karnik (S)

Pyxant Labs, Colorado Springs, CO 80907, USA.

Michael Brown (M)

Q2 Solutions, Marietta, GA 30067, USA.

Steve Lowes (S)

Q2 Solutions, Ithaca, NY 14850, USA.

Ira DuBey (I)

Smithers Avanza, Gaithersburg, MD 20878, USA.

Nadia Kulagina (N)

Smithers Avanza, Gaithersburg, MD 20878, USA.

John Lindsay (J)

SNBL USA, Everett, WA 98203, USA; currently part of Altasciences.

Clark Williard (C)

Syneos Health, Princeton, NJ 08540, USA.

Hao Wang (H)

TETRAQ, Herston, QLD 4029, Australia.

Michele Malone (M)

Worldwide Clinical Trials, Austin, TX 78754, USA.

Edward Wells (E)

Worldwide Clinical Trials, Austin, TX 78754, USA.

Xinping Fang (X)

WuXi Apptec, Plainsboro, NJ 08536, USA.

Marc Moussallie (M)

WuXi Apptec, Plainsboro, NJ 08536, USA.

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