High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.

Cell Line HLA-A2 Antigen / immunology High-Throughput Screening Assays Humans Kinetics Major Histocompatibility Complex / immunology Peptides / immunology Receptors, Antigen, T-Cell / immunology

Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
19 07 2019
Historique:
received: 13 08 2018
accepted: 21 06 2019
entrez: 21 7 2019
pubmed: 22 7 2019
medline: 2 6 2020
Statut: ppublish

Résumé

Major histocompatibility complex (MHC) class I molecules present short peptide ligands on the cell surface for interrogation by cytotoxic CD8

Identifiants

DOI: 10.1126/sciimmunol.aav0860 PMID: 31324691
pubmed: 31324691
pii: 4/37/eaav0860
doi: 10.1126/sciimmunol.aav0860
pii:
doi:

Substances chimiques

HLA-A*02:01 antigen 0
HLA-A2 Antigen 0
Peptides 0
Receptors, Antigen, T-Cell 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Auteurs

Andreas Moritz (A)

Department of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany. andreas.moritz@student.uni-tuebingen.de maurer@immatics.com.
Immatics Biotechnologies GmbH, Tübingen, Germany.
ORCID: 0000-0002-8097-7780

Raghavendra Anjanappa (R)

Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
ORCID: 0000-0003-0049-711X

Claudia Wagner (C)

Immatics Biotechnologies GmbH, Tübingen, Germany.
ORCID: 0000-0002-7311-2236

Sebastian Bunk (S)

Immatics Biotechnologies GmbH, Tübingen, Germany.

Martin Hofmann (M)

Immatics Biotechnologies GmbH, Tübingen, Germany.
ORCID: 0000-0002-8870-6512

Gabriele Pszolla (G)

Immatics Biotechnologies GmbH, Tübingen, Germany.

Ankur Saikia (A)

Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
ORCID: 0000-0002-7169-5765

Maria Garcia-Alai (M)

European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, D-22607 Hamburg, Germany.

Rob Meijers (R)

European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, D-22607 Hamburg, Germany.
ORCID: 0000-0003-2872-6279

Hans-Georg Rammensee (HG)

Department of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
ORCID: 0000-0003-1614-2647

Sebastian Springer (S)

Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
ORCID: 0000-0002-5527-6149

Dominik Maurer (D)

Immatics Biotechnologies GmbH, Tübingen, Germany. andreas.moritz@student.uni-tuebingen.de maurer@immatics.com.
ORCID: 0000-0001-5273-7192

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-A › Antigène HLA-A2 › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Techniques d'investigation › Tests de criblage à haut débit › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Phénomènes du système immunitaire › Phénomènes immunogénétiques › Complexe majeur d'histocompatibilité › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › High-throughput peptide-MHC complex generation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › High-throughput peptide-MHC complex generation...