Benefits of cooperation among large-scale cohort studies and human biomonitoring projects in environmental health research: An exercise in blood lead analysis of the Environment and Child Health International Birth Cohort Group.


Journal

International journal of hygiene and environmental health
ISSN: 1618-131X
Titre abrégé: Int J Hyg Environ Health
Pays: Germany
ID NLM: 100898843

Informations de publication

Date de publication:
09 2019
Historique:
received: 10 04 2019
revised: 09 07 2019
accepted: 11 07 2019
pubmed: 23 7 2019
medline: 24 4 2020
entrez: 23 7 2019
Statut: ppublish

Résumé

A number of prospective cohort studies are ongoing worldwide to investigate the impact of foetal and neonatal exposures to chemical substances on child health. To assess multiple exposure (mixture) effects and low prevalence health outcomes it is useful to pool data from several studies and conduct mega-data-analysis. To discuss a path towards data harmonization, representatives from several large-scale birth cohort studies and a biomonitoring programme formed a collaborative group, the Environment and Child Health International Birth Cohort Group (ECHIBCG). In this study, an intra-laboratory trial was performed to harmonize existing blood lead measurements within the groups' studies. Then, decentralized analyses were conducted in individual countries' laboratories to evaluate blood lead levels (BLL) in each study. The measurements of pooled BLL samples in French, German and three Japanese laboratories resulted in an overall mean blood lead concentration of 8.66 μg l

Identifiants

pubmed: 31327570
pii: S1438-4639(19)30314-1
doi: 10.1016/j.ijheh.2019.07.005
pmc: PMC6732228
mid: NIHMS1535723
pii:
doi:

Substances chimiques

Environmental Pollutants 0
Lead 2P299V784P

Types de publication

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1059-1067

Subventions

Organisme : NIEHS NIH HHS
ID : N01ES75558
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS047537
Pays : United States

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier GmbH.. All rights reserved.

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Auteurs

Shoji F Nakayama (SF)

Japan Environment and Children's Study Programme Office, National Institute for Environmental Studies, Tsukuba, Japan. Electronic address: fabre@nies.go.jp.

Carolina Espina (C)

International Agency for Research on Cancer (IARC), Section of Environment and Radiation, Lyon, France.

Michihiro Kamijima (M)

Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Per Magnus (P)

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.

Marie-Aline Charles (MA)

Ined, Inserm, EFS, Elfe Joint Unit, Paris, France.

Jun Zhang (J)

Ministry of Education - Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Birgit Wolz (B)

Federal Ministry for the Environment, Nature Conservation and Nuclear Safety, Bonn, Germany.

André Conrad (A)

German Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.

Aline Murawski (A)

German Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.

Miyuki Iwai-Shimada (M)

Japan Environment and Children's Study Programme Office, National Institute for Environmental Studies, Tsukuba, Japan.

Cécile Zaros (C)

Ined, Inserm, EFS, Elfe Joint Unit, Paris, France.

Ida Henriette Caspersen (IH)

Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Marike Kolossa-Gehring (M)

German Environment Agency, Section Toxicology, Health Related Monitoring, Berlin, Germany.

Helle Margrete Meltzer (HM)

Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Sjurdur F Olsen (SF)

Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, 02115, USA.

Ruth A Etzel (RA)

Milken Institute School of Public Health, The George Washington University, Washington, DC, USA.

Joachim Schüz (J)

International Agency for Research on Cancer (IARC), Section of Environment and Radiation, Lyon, France.

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Classifications MeSH