Quelles sont les options pour une transfusion sanguine fœtale ?
Les transfusions peuvent être réalisées par voie intraveineuse ou par cordon ombilical.
Transfusion sanguineCordon ombilical
#5
Le traitement de l'incompatibilité sanguine fœtale est-il possible ?
Oui, des traitements comme l'immunoglobuline anti-D peuvent prévenir des complications.
Incompatibilité sanguineImmunoglobuline
Complications
5
#1
Quelles complications peuvent survenir avec le sang fœtal ?
Des complications comme l'hypoxie, l'anémie ou des malformations peuvent survenir.
HypoxieAnémie
#2
Le sang fœtal peut-il causer des problèmes à la naissance ?
Oui, des problèmes comme la jaunisse ou des troubles respiratoires peuvent se manifester.
JaunisseTroubles respiratoires
#3
Quels sont les risques d'une transfusion sanguine fœtale ?
Les risques incluent des infections, des réactions transfusionnelles ou des saignements.
Transfusion sanguineInfections
#4
Comment l'incompatibilité sanguine affecte-t-elle le fœtus ?
Elle peut entraîner des anémies sévères ou des dommages cérébraux si non traitée.
Incompatibilité sanguineAnémie
#5
Quelles sont les conséquences d'une hypoxie fœtale ?
L'hypoxie peut entraîner des lésions cérébrales, des retards de développement ou la mort.
HypoxieLésions cérébrales
Facteurs de risque
5
#1
Quels facteurs augmentent le risque d'anomalies sanguines fœtales ?
L'âge maternel avancé, des antécédents familiaux et certaines infections augmentent le risque.
Âge maternelAntécédents familiaux
#2
Le tabagisme affecte-t-il le sang fœtal ?
Oui, le tabagisme peut réduire l'apport en oxygène et nuire au développement fœtal.
TabagismeDéveloppement fœtal
#3
Les maladies chroniques influencent-elles le sang fœtal ?
Oui, des maladies comme le diabète ou l'hypertension peuvent affecter la circulation sanguine fœtale.
DiabèteHypertension
#4
Les infections maternelles sont-elles un risque pour le sang fœtal ?
Oui, des infections comme la rubéole ou le VIH peuvent avoir des conséquences graves.
Infections maternellesRubéole
#5
Le stress maternel impacte-t-il le sang fœtal ?
Oui, le stress peut affecter la circulation sanguine et le bien-être fœtal.
StressBien-être fœtal
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"@type": "Question",
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"position": 18,
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"@type": "Answer",
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},
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"name": "Quelles sont les conséquences d'une hypoxie fœtale ?",
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The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2020-08-17
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2020-08-17
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2020-08-17
Fluoride exposure during pregnancy has been associated with various effects on offspring, including changes in behavior and IQ. To provide clues to possible mechanisms by which fluoride may affect hum...
To identify changes in cord blood proteins associated with maternal serum fluoride concentration in pregnant women....
The proteomes of 19 archived second-trimester cord blood samples from women living in northern California, USA, and having varied serum fluoride concentrations, were analyzed by quantitative mass spec...
Pathway analyses showed significant increases in process related to reactive oxygen species and cellular oxidant detoxification, associated with increasing maternal serum fluoride concentrations. Path...
Maternal fluoride exposure, as measured by serum fluoride concentrations in a small, but representative sample of women from northern California, USA, showed significant changes in the second trimeste...
Obstructive sleep apnea (OSA) is quite prevalent during pregnancy and is associated with adverse perinatal outcomes, but its potential influence on fetal development remains unclear. This study invest...
Hemangioblasts give rise to endothelial progenitor cells (EPCs), which also express the cell surface markers CD133 and c-kit. They may differentiate into the outgrowth endothelial cells (OECs) that co...
Recent evidence has revealed associations between endocrine-disrupting chemicals (EDCs) and placental insufficiency due to altered placental growth, syncytialization, and trophoblast invasion. However...
Disturbances in maternal, placental, and fetal metabolism are associated with developmental outcomes. Associations of maternal, placental, and fetal metabolism with subsequent neurodevelopmental outco...
To investigate the metabolic associations within the maternal-placental-fetal unit and subsequent neurodevelopmental outcomes in younger siblings of children with autism spectrum disorder (ASD)....
This cohort study was conducted within a subset of the Markers of Autism Risk in Babies, Learning Early Signs (MARBLES) cohort. MARBLES is a prospective birth cohort of younger siblings of children wi...
Quantitative metabolomics analysis was conducted on maternal third trimester serum, as well as placental tissue and umbilical cord serum collected at delivery....
Using the Autism Diagnostic Observation Schedule and Mullen Scales of Early Learning, outcomes were classified as ASD, other nontypical development (non-TD), and typical development (TD)....
This analysis included 100 maternal serum samples, 141 placental samples, and 124 umbilical cord serum samples from 152 pregnancies (median [IQR] maternal age, 34.6 [30.8-38.3] years; median [IQR] ges...
In this cohort study of children with high familial risk of ASD, placental and cord serum metabolism at delivery were highly correlated. Furthermore, placental and cord serum metabolic profiles were a...
A previous study suggested that fetal inheritance of chromosomally integrated human herpesvirus 6 (ici-HHV6) is associated with the hypertensive pregnancy disorder preeclampsia (PE). We aimed to study...
Humans are widely exposed to perfluoroalkyl substances (PFAS), which have been found to be associated with various adverse birth outcomes. As blood pressure (BP) is an important parameter reflecting c...
PFAS in umbilical cord blood samples after birth were measured with high-performance liquid chromatography/tandem mass spectrometry in the Shanghai Birth Cohort. BP was measured at 4 years of age in t...
A total of 129 mother-child pairs were included in our analysis. In multiple linear regressions, we observed that long-chain PFAS, mainly including perfluorooctane sulfonate (PFOS), perfluorodecanoic ...
Our findings suggested that umbilical blood PFAS exposure was negatively associated with BP in offspring at 4 years of age, including SBP, DBP, and MAP....
Repeated transfusions in preterm neonates with anemia of prematurity replace fetal hemoglobin (HbF) with adult Hb (HbA), which has a low oxygen affinity. The reduction of HbF is associated with a high...
To assess whether HbF and HbA are differently associated with cerebral tissue oxygenation in preterm neonates....
This cohort study was a single-center, pilot study on cerebral oxygenation kinetics in preterm neonates with a gestational age between 24.0 weeks and 27.9 weeks who were admitted to the neonatal inten...
Transfusion with A-RBCs or CB-RBCs....
The main outcome was the kinetics of cerebral regional oxygen saturation (crSO2) and cerebral fraction of tissue oxygen extraction (cFTOE) associated with A-RBC or CB-RBC transfusions. Cerebral NIRS m...
Of 23 randomized neonates, 17 (11 male [64.7%]; median gestational age at birth, 25.6 weeks [IQR, 25.3-26.1 weeks]) with a median birth weight of 840 g (IQR, 580-900 g) were included in the study; NIR...
The findings of this cohort study suggest that A-RBC transfusions may be associated with more oxygen delivery to cerebral tissues of preterm neonates than transfusions from CB-RBCs. This finding may e...
Hematopoietic stem progenitor cells (HSPCs) undergo phenotypical and functional changes during their emergence and development. Although the molecular programs governing the development of human hemat...
In this study, we comprehensively described the proteomics of HSPCs in the human fetal liver (FL), umbilical cord blood (UCB), and adult bone marrow (aBM). The metabolic state of human HSPCs was asses...
We investigated the metabolomic landscape of human HSPCs from the fetal, perinatal, and adult developmental stages by in-depth quantitative proteomics and predicted a metabolic switch from the oxidati...
The metabolic landscape of human HSPCs at three developmental stages (FL, UCB, and aBM), combined with proteomics and functional validations, substantially extends our understanding of HSC metabolic r...
Fetal growth restriction (FGR) is a significant contributor to negative pregnancy and postnatal developmental outcomes. Currently, the exact pathological mechanism of FGR remains unknown. This study a...
In this study, 11 healthy pregnant women and nine pregnant women with FGR were divided into Control group and FGR group based on the health status. Umbilical cord blood, maternal serum, feces, and pla...
The top 5 mRNA genes in FGR were altered with the downregulation of TRIM34, DEFA3, DEFA1B, DEFA1, and QPC, and the upregulation of CHPT1, SMOX, FAM83A, GDF15, and NAPG in newborn umbilical cord blood,...
Metabolites (METHIONINE, alanine) as well as microbiota (...