Fetal Thoracic Circumference and Lung Volume and Their Relation to Fetal Size and Pulmonary Artery Blood Flow.
Doppler
PreventADALL
fetal
lung volume
pulmonary artery
thoracic circumference
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
revised:
17
06
2021
received:
04
11
2020
accepted:
03
07
2021
pubmed:
22
7
2021
medline:
16
3
2022
entrez:
21
7
2021
Statut:
ppublish
Résumé
Research on early origins of lung disease suggests the need for studying the relationships of thoracic and lung size with fetal size and pulmonary circulation. The primary aim of this study is therefore to explore the associations between fetal thoracic circumference, lung volume, and fetal size. We also aim to assess if lung volume and thoracic circumference are associated with fetal pulmonary artery blood flow velocity measures. Cross-sectional assessment of singleton pregnancies from the general population (n = 447) at 30 gestational weeks (GW) was performed using ultrasound measurement of fetal thoracic circumference, lung volume, head and abdominal circumference, and femur length. We obtained Doppler blood flow velocity measures from the proximal branches of the fetal pulmonary artery. Associations between variables were studied using Pearson's correlation and multiple linear regression analyses. Both thoracic circumference and lung volume correlated with fetal size measures, ranging from r = 0.64 between thoracic circumference and abdominal circumference, to r = 0.28 between lung volume and femur length. Adjustment for gestational age, maternal nicotine use, pre-pregnancy body mass index, and fetal sex marginally influenced the associations with abdominal circumference. The correlations of thoracic circumference and lung volume with pulmonary artery blood flow velocity measures were weak (r ≤ 0.17). We found moderate to low correlation between thoracic circumference, lung volume, and fetal size at 30 GW. The closest relationship was with the abdominal circumference. We found low correlations of thoracic circumference and lung volume with pulmonary artery blood flow velocity measures.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
985-993Informations de copyright
© 2021 The Authors. Journal of Ultrasound in Medicine published by Wiley Periodicals LLC on behalf of American Institute of Ultrasound in Medicine.
Références
den Dekker HT, Jaddoe VWV, Reiss IK, de Jongste JC, Duijts L. Fetal and infant growth patterns and risk of lower lung function and asthma. The generation R study. Am J Respir Crit Care Med 2018; 197:183-192. https://doi.org/10.1164/rccm.201703-0631OC.
Turner S, Prabhu N, Danielan P, et al. First- and second-trimester fetal size and asthma outcomes at age 10 years. Am J Respir Crit Care Med 2011; 184:407-413. https://doi.org/10.1164/rccm.201012-2075OC.
Kooijman MN, van Meel ER, EAP S, et al. Fetal umbilical, cerebral and pulmonary blood flow patterns in relation to lung function and asthma in childhood. The generation R study. Pediatr Allergy Immunol 2019; 30:443-450. https://doi.org/10.1111/pai.13044.
Yoshimura S, Masuzaki H, Gotoh H, Fukuda H, Ishimaru T. Ultrasonographic prediction of lethal pulmonary hypoplasia: comparison of eight different ultrasonographic parameters. Am J Obstet Gynecol 1996; 175:477-483.
Prendergast M, Rafferty GF, Davenport M, et al. Three-dimensional ultrasound fetal lung volumes and infant respiratory outcome: a prospective observational study. BJOG 2011; 118:608-614. https://doi.org/10.1111/j.1471-0528.2010.02841.x.
DeVore GR, Horenstein J, Platt LD. Fetal echocardiography. VI. Assessment of cardiothoracic disproportion-a new technique for the diagnosis of thoracic hypoplasia. Am J Obstet Gynecol 1986; 155:1066-1071.
Chang CH, Yu CH, Chang FM, Ko HC, Chen HY. Volumetric assessment of normal fetal lungs using three-dimensional ultrasound. Ultrasound Med Biol 2003; 29:935-942. https://doi.org/10.1016/s0301-5629(03)00902-5.
Britto IS, Tedesco GD, Herbst SR, et al. New anatomical landmarks to study the relationship between fetal lung area and thoracic circumference by three-dimensional ultrasonography. J Matern Fetal Neonatal Med 2012; 25:1927-1932. https://doi.org/10.3109/14767058.2012.667176.
Schittny JC. Development of the lung. Cell Tissue Res 2017; 367:427-444. https://doi.org/10.1007/s00441-016-2545-0.
Tchirikov M, Kertschanska S, Sturenberg HJ, Schroder HJ. Liver blood perfusion as a possible instrument for fetal growth regulation. Placenta 2002; 23:S153-S158. https://doi.org/10.1053/plac.2002.0810.
Kooijman MN, Bakker H, van der Heijden AJ, et al. Childhood kidney outcomes in relation to fetal blood flow and kidney size. J Am Soc Nephrol 2014; 25:2616-2624. https://doi.org/10.1681/asn.2013070746.
Laudy JA, Tibboel D, Robben SG, de Krijger RR, de Ridder MA, Wladimiroff JW. Prenatal prediction of pulmonary hypoplasia: clinical, biometric, and Doppler velocity correlates. Pediatrics 2002; 109:250-258.
Cruz-Martinez R, Castanon M, Moreno-Alvarez O, Acosta-Rojas R, Martinez JM, Gratacos E. Usefulness of lung-to-head ratio and intrapulmonary arterial Doppler in predicting neonatal morbidity in fetuses with congenital diaphragmatic hernia treated with fetoscopic tracheal occlusion. Ultrasound Obstet Gynecol 2013; 41:59-65. https://doi.org/10.1002/uog.11212.
Yamamoto Y, Hirose A, Jain V, Hornberger LK. Branch pulmonary artery Doppler parameters predict early survival-non-survival in premature rupture of membranes. J Perinatol 2020; 40:1821-1827. https://doi.org/10.1038/s41372-020-00817-6.
Chaoui R, Taddei F, Rizzo G, Bast C, Lenz F, Bollmann R. Doppler echocardiography of the main stems of the pulmonary arteries in the normal human fetus. Ultrasound Obstet Gynecol 1998; 11:173-179. https://doi.org/10.1046/j.1469-0705.1998.11030173.x.
Laudy JAM, De Ridder MAJ, Wladimiroff JW. Doppler velocimetry in branch pulmonary arteries of Normal human fetuses during the second half of gestation. Pediatr Res 1997; 41:897. https://doi.org/10.1203/00006450-199706000-00016.
Rasanen J, Huhta JC, Weiner S, Wood DC, Ludomirski A. Fetal branch pulmonary arterial vascular impedance during the second half of pregnancy. Am J Obstet Gynecol 1996; 174:1441-1449.
Lodrup Carlsen KC, Rehbinder EM, Skjerven HO, et al. Preventing atopic dermatitis and ALLergies in children-the PreventADALL study. Allergy 2018; 73:2063-2070. https://doi.org/10.1111/all.13468.
Johnsen SL, Wilsgaard T, Rasmussen S, Sollien R, Kiserud T. Longitudinal reference charts for growth of the fetal head, abdomen and femur. Eur J Obstet Gynecol Reprod Biol 2006; 127:172-185. https://doi.org/10.1016/j.ejogrb.2005.10.004.
Moeglin D, Talmant C, Duyme M, Lopez AC. Fetal lung volumetry using two- and three-dimensional ultrasound. Ultrasound Obstet Gynecol 2005; 25:119-127. https://doi.org/10.1002/uog.1799.
Hilde K, Lødrup Carlsen KC, Haugen G. Doppler measures of blood flow in right and left branches of the fetal pulmonary artery. J Matern Fetal Neonatal Med 2020; 17:1-4. https://doi.org/10.1080/14767058.2020.1807509.
Gerards FA, Engels MA, Twisk JW, van Vugt JM. Normal fetal lung volume measured with three-dimensional ultrasound. Ultrasound Obstet Gynecol 2006; 27:134-144. https://doi.org/10.1002/uog.2672.
Peralta CF, Cavoretto P, Csapo B, Vandecruys H, Nicolaides KH. Assessment of lung area in normal fetuses at 12-32 weeks. Ultrasound Obstet Gynecol 2005; 26:718-724. https://doi.org/10.1002/uog.2651.
Roberts AB, Mitchell JM. Direct ultrasonographic measurement of fetal lung length in normal pregnancies and pregnancies complicated by prolonged rupture of membranes. Am J Obstet Gynecol 1990; 163:1560-1566.
Szpinda M, Siedlaczek W, Szpinda A, Wozniak A, Mila-Kierzenkowska C, Badura M. Quantitative anatomy of the growing lungs in the human fetus. BioMed research international 2015; 2015:362781. https://doi.org/10.1155/2015/362781.
Ruano R, Joubin L, Aubry MC, et al. A nomogram of fetal lung volumes estimated by 3-dimensional ultrasonography using the rotational technique (virtual organ computer-aided analysis). J Ultrasound Med 2006; 25:701-709.
Kiserud T, Piaggio G, Carroli G, et al. The World Health Organization fetal growth charts: a multinational longitudinal study of ultrasound biometric measurements and estimated fetal weight. PLoS Med 2017; 14:e1002220. https://doi.org/10.1371/journal.pmed.1002220.
Gordijn SJ, Beune IM, Thilaganathan B, et al. Consensus definition of fetal growth restriction: a Delphi procedure. Ultrasound Obstet Gynecol 2016; 48:333-339. https://doi.org/10.1002/uog.15884.
Knight-Agarwal CR, Mellor D, Georgousopoulos EN, Krause B, Coghlan S. Maternal body mass index, smoking status and small for gestational age: an Australian retrospective cohort study. Public Health 2020; 185:381-385. https://doi.org/10.1016/j.puhe.2020.05.029.
Habash S, Laser KT, Moosmann J, et al. Normal values of the pulmonary artery acceleration time (PAAT) and the right ventricular ejection time (RVET) in children and adolescents and the impact of the PAAT/RVET-index in the assessment of pulmonary hypertension. Int J Cardiovasc Imaging 2019; 35:295-306. https://doi.org/10.1007/s10554-019-01540-w.
Laudy JA, de Ridder MA, Wladimiroff JW. Doppler velocimetry in branch pulmonary arteries of normal human fetuses during the second half of gestation. Pediatr Res 1997; 41:897-901. https://doi.org/10.1203/00006450-199706000-00016.
Morin FC 3rd, Egan EA. Pulmonary hemodynamics in fetal lambs during development at normal and increased oxygen tension. J Appl Physiol (Bethesda, MD: 1985) 1992; 73:213-218. https://doi.org/10.1152/jappl.1992.73.1.213.
Kasprian G, Balassy C, Brugger PC, Prayer D. MRI of normal and pathological fetal lung development. Eur J Radiol 2006; 57:261-270. https://doi.org/10.1016/j.ejrad.2005.11.031.
Turner SW, Devereux G. Fetal ultrasound: shedding light or casting shadows on the fetal origins of airway disease. Am J Respir Crit Care Med 2012; 185:694-695. https://doi.org/10.1164/rccm.201202-0180ED.