Myocardial ischemia and coronary disease in heart failure.

Coronary Artery Disease / complications Coronary Circulation Coronary Vessels / pathology Disease Progression Heart Failure / complications Humans Myocardial Ischemia / complications Randomized Controlled Trials as Topic Risk Factors
Coronary artery disease Heart failure Microvascular dysfunction Myocardial ischemia Wall stress

Journal

Heart failure reviews
ISSN: 1573-7322
Titre abrégé: Heart Fail Rev
Pays: United States
ID NLM: 9612481

Informations de publication

Date de publication:
01 2020
Historique:
pubmed: 25 7 2019
medline: 5 11 2020
entrez: 24 7 2019
Statut: ppublish

Résumé

Heart failure is a complex clinical syndrome and represents the final path of numerous heart diseases. Coronary artery disease is recognized as the primary risk factor for heart failure development, being the main etiological factor in more than 50% of heart failure patients in North America and Europe. Regardless of overt coronary artery disease, myocardial ischemia is a common finding in failing hearts, likely due to structural or functional coronary circulation alterations. Ischemia is a self-propagating process which irreversibly impairs the cardiac function and negatively impacts prognosis. Thus, a better and thorough understanding of myocardial ischemia pathophysiology in heart failure would likely lead to significantly improved outcomes in these patients. This review aims to describe the mechanisms of myocardial ischemia and coronary artery disease in heart failure, focusing on coronary circulation dysfunctions due to increased parietal stress or non-obstructive coronary disease, and discussing the association and management of coronary artery disease in patients with heart failure.

Identifiants

DOI: 10.1007/s10741-019-09831-z PMID: 31332663
pubmed: 31332663
doi: 10.1007/s10741-019-09831-z
pii: 10.1007/s10741-019-09831-z
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

53-65

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Auteurs

Beniamino R Pagliaro (BR)

Cardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.

Francesco Cannata (F)

Cardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy.

Giulio G Stefanini (GG)

Cardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. giulio.stefanini@hunimed.eu.
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Pieve Emanuele, Milan, Italy. giulio.stefanini@hunimed.eu.
ORCID: 0000-0002-3558-6967

Leonardo Bolognese (L)

Dipartimento Cardio Neuro Vascolare, Ospedale San Donato, Arezzo, Italy.

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Classifications MeSH

questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Ischémie myocardique › Maladie coronarienne › Maladie des artères coronaires › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Circulation sanguine › Circulation coronarienne › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Veines › Vaisseaux coronaires › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Évolution de la maladie › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Ischémie myocardique › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Myocardial ischemia and coronary disease in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Myocardial ischemia and coronary disease in...