Structural Destabilization of Azurin by Imidazolium Chloride Ionic Liquids in Aqueous Solution.


Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
15 08 2019
Historique:
pubmed: 25 7 2019
medline: 1 8 2020
entrez: 24 7 2019
Statut: ppublish

Résumé

Alkyl imidazolium chloride ionic liquids (ILs) have been used for numerous biochemical applications. Their hydrophobicity can be tuned by changing the alkyl chain length, and longer-chain ILs can form micelles in aqueous solution. We have investigated the effects of imidazolium chloride ILs on the structure and stability of azurin, which is a very stable Cu

Identifiants

pubmed: 31335143
doi: 10.1021/acs.jpcb.9b04113
doi:

Substances chimiques

Bacterial Proteins 0
Enzyme Inhibitors 0
Imidazoles 0
Ionic Liquids 0
Micelles 0
Water 059QF0KO0R
Azurin 12284-43-4
imidazole 7GBN705NH1

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

6933-6945

Auteurs

Arusha Acharyya (A)

Department of Chemistry , University of Pennsylvania , 231 S. 34 Street , Philadelphia , Pennsylvania 19104 , United States.

David DiGiuseppi (D)

Department of Chemistry , Drexel University , 32 S. 32nd Street , Philadelphia , Pennsylvania 19104 , United States.

Brittany L Stinger (BL)

Department of Chemistry and Biochemistry , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.

Reinhard Schweitzer-Stenner (R)

Department of Chemistry , Drexel University , 32 S. 32nd Street , Philadelphia , Pennsylvania 19104 , United States.

Timothy D Vaden (TD)

Department of Chemistry and Biochemistry , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.

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Classifications MeSH