Brain histamine H
Adult
Brain
/ diagnostic imaging
Cross-Over Studies
Double-Blind Method
Healthy Volunteers
Histamine H1 Antagonists, Non-Sedating
/ administration & dosage
Humans
Loratadine
/ administration & dosage
Male
Positron-Emission Tomography
/ methods
Receptors, Histamine H1
/ metabolism
Sleepiness
Young Adult
brain H1 receptor occupancy
desloratadine
positron emission tomography
Journal
Pharmacology research & perspectives
ISSN: 2052-1707
Titre abrégé: Pharmacol Res Perspect
Pays: United States
ID NLM: 101626369
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
received:
20
03
2019
revised:
30
05
2019
accepted:
10
06
2019
entrez:
25
7
2019
pubmed:
25
7
2019
medline:
30
4
2020
Statut:
epublish
Résumé
Some histamine H
Identifiants
pubmed: 31338198
doi: 10.1002/prp2.499
pii: PRP2499
pmc: PMC6624455
doi:
Substances chimiques
Histamine H1 Antagonists, Non-Sedating
0
Receptors, Histamine H1
0
Loratadine
7AJO3BO7QN
desloratadine
FVF865388R
Types de publication
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e00499Déclaration de conflit d'intérêts
This study was funded by KYORIN Pharmaceutical Co., Ltd (Tokyo, Japan). The principal investigator and corresponding author (KY) received research grants from Meiji Seika Pharma (Tokyo, Japan), GlaxoSmithKline (Brentford, UK), Taiho Pharma (Tokyo, Japan), Sanofi (Paris, France) and KYORIN Pharmaceutical Company. In the last 3 years, KY received honoraria from manufacturers of second‐generation antihistamines, including Sanofi, GlaxoSmithKline, Kyowa‐Kirin (Tokyo, Japan), Taiho Pharma, Meiji Seika Pharma and Mitsubishi Tanabe Pharma (Osaka, Japan). The contents regarding all aspects of the review were provided by all the academic authors without consulting with the pharmaceutical companies.
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