Evidence for West Nile Virus and Usutu Virus Infections in Wild and Resident Birds in Germany, 2017 and 2018.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
23 07 2019
Historique:
received: 27 06 2019
revised: 18 07 2019
accepted: 18 07 2019
entrez: 26 7 2019
pubmed: 26 7 2019
medline: 18 8 2020
Statut: epublish

Résumé

Wild birds play an important role as reservoir hosts and vectors for zoonotic arboviruses and foster their spread. Usutu virus (USUV) has been circulating endemically in Germany since 2011, while West Nile virus (WNV) was first diagnosed in several bird species and horses in 2018. In 2017 and 2018, we screened 1709 live wild and zoo birds with real-time polymerase chain reaction and serological assays. Moreover, organ samples from bird carcasses submitted in 2017 were investigated. Overall, 57 blood samples of the live birds (2017 and 2018), and 100 organ samples of dead birds (2017) were positive for USUV-RNA, while no WNV-RNA-positive sample was found. Phylogenetic analysis revealed the first detection of USUV lineage Europe 2 in Germany and the spread of USUV lineages Europe 3 and Africa 3 towards Northern Germany. USUV antibody prevalence rates were high in Eastern Germany in both years. On the contrary, in Northern Germany, high seroprevalence rates were first detected in 2018, with the first emergence of USUV in this region. Interestingly, high WNV-specific neutralizing antibody titers were observed in resident and short-distance migratory birds in Eastern Germany in 2018, indicating the first signs of a local WNV circulation.

Identifiants

pubmed: 31340516
pii: v11070674
doi: 10.3390/v11070674
pmc: PMC6669720
pii:
doi:

Substances chimiques

Antibodies, Neutralizing 0
Antibodies, Viral 0

Types de publication

Historical Article Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Friederike Michel (F)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.
German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel, 17493 Greifswald-Insel Riems, Germany.

Michael Sieg (M)

Institute of Virology (Faculty of veterinary medicine), Leipzig University, An den Tierkliniken 29, D-04103 Leipzig, Germany.

Dominik Fischer (D)

Clinic for Birds, Reptiles, Amphibians and Fish, Justus Liebig University Giessen, Frankfurter Straße 91, D-35392 Giessen, Germany.

Markus Keller (M)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

Martin Eiden (M)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

Maximilian Reuschel (M)

Clinic for Small Mammals, Reptiles and Birds, University of Veterinary Medicine Hannover, Foundation, Bünteweg 9, D-30559 Hannover, Germany.

Volker Schmidt (V)

Clinic for Birds and Reptiles (Faculty of veterinary medicine), Leipzig University, An den Tierkliniken 17, D-04103 Leipzig, Germany.

Rebekka Schwehn (R)

Clinic for Small Mammals, Reptiles and Birds, University of Veterinary Medicine Hannover, Foundation, Bünteweg 9, D-30559 Hannover, Germany.
Seehundstation Nationalpark-Haus Norden-Norddeich, Dörper Weg 24, D-26506 Norden, Germany.

Monika Rinder (M)

Clinic for Birds, Small Mammals, Reptiles and Ornamental Fish, Centre for Clinical Veterinary Medicine, Ludwig Maximilians University Munich, Sonnenstraße 18, D-85764 Oberschleißheim, Germany.

Sylvia Urbaniak (S)

Birds of Prey Rehab Center Rhineland (Greifvogelhilfe Rheinland)/Tierarztpraxis Sudhoff, Hehnerholt 105, D-41069 Mönchengladbach, Germany.

Kerstin Müller (K)

Department of Veterinary Medicine, Small Animal Clinic, Freie Universität Berlin, Oertzenweg 19 b, D-14163 Berlin, Germany.

Martina Schmoock (M)

Wildpark Schwarze Berge GmbH & Co. KG, Am Wildpark 1, D-21224 Rosengarten, Germany.
Tiermedizin am Rothenbaum, Rothenbaumchaussee 195, D-20149 Hamburg, Germany.

Renke Lühken (R)

Bernhard-Nocht-Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Hemorrhagic Fever Reference and Research, Bernhardt-Nocht Straße 74, D-20359 Hamburg, Germany.

Patrick Wysocki (P)

Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Epidemiology, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

Christine Fast (C)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

Michael Lierz (M)

Clinic for Birds, Reptiles, Amphibians and Fish, Justus Liebig University Giessen, Frankfurter Straße 91, D-35392 Giessen, Germany.

Rüdiger Korbel (R)

Clinic for Birds, Small Mammals, Reptiles and Ornamental Fish, Centre for Clinical Veterinary Medicine, Ludwig Maximilians University Munich, Sonnenstraße 18, D-85764 Oberschleißheim, Germany.

Thomas W Vahlenkamp (TW)

Institute of Virology (Faculty of veterinary medicine), Leipzig University, An den Tierkliniken 29, D-04103 Leipzig, Germany.

Martin H Groschup (MH)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.
German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel, 17493 Greifswald-Insel Riems, Germany.

Ute Ziegler (U)

Friedrich-Loeffler Insitut (FLI), Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany. ute.ziegler@fli.de.
German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel, 17493 Greifswald-Insel Riems, Germany. ute.ziegler@fli.de.

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