Venoms of Iranian Scorpions (Arachnida, Scorpiones) and Their Potential for Drug Discovery.
Animals
Antimicrobial Cationic Peptides
/ biosynthesis
Antineoplastic Agents
/ chemistry
Arthropod Proteins
/ biosynthesis
Drug Discovery
/ methods
Gene Expression
Humans
Ion Channels
/ agonists
Iran
Metalloproteases
/ biosynthesis
Phospholipases A2
/ biosynthesis
Phylogeny
Scorpion Stings
/ physiopathology
Scorpion Venoms
/ biosynthesis
Scorpions
/ chemistry
Serine Proteinase Inhibitors
/ biosynthesis
Species Specificity
Iran
fauna
scorpion
toxin
venom
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
23 Jul 2019
23 Jul 2019
Historique:
received:
16
03
2019
revised:
16
07
2019
accepted:
20
07
2019
entrez:
26
7
2019
pubmed:
26
7
2019
medline:
28
12
2019
Statut:
epublish
Résumé
Scorpions, a characteristic group of arthropods, are among the earliest diverging arachnids, dating back almost 440 million years. One of the many interesting aspects of scorpions is that they have venom arsenals for capturing prey and defending against predators, which may play a critical role in their evolutionary success. Unfortunately, however, scorpion envenomation represents a serious health problem in several countries, including Iran. Iran is acknowledged as an area with a high richness of scorpion species and families. The diversity of the scorpion fauna in Iran is the subject of this review, in which we report a total of 78 species and subspecies in 19 genera and four families. We also list some of the toxins or genes studied from five species, including
Identifiants
pubmed: 31340554
pii: molecules24142670
doi: 10.3390/molecules24142670
pmc: PMC6680535
pii:
doi:
Substances chimiques
Antimicrobial Cationic Peptides
0
Antineoplastic Agents
0
Arthropod Proteins
0
Ion Channels
0
Scorpion Venoms
0
Serine Proteinase Inhibitors
0
Phospholipases A2
EC 3.1.1.4
Metalloproteases
EC 3.4.-
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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