Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
03 03 2020
Historique:
received: 25 03 2019
accepted: 12 07 2019
pubmed: 26 7 2019
medline: 7 1 2021
entrez: 26 7 2019
Statut: ppublish

Résumé

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. NCT03048643.

Identifiants

pubmed: 31342057
pii: 5538253
doi: 10.1093/cid/ciz654
pmc: PMC7931831
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anti-Infective Agents 0
Buprenorphine 40D3SCR4GZ

Banques de données

ClinicalTrials.gov
['NCT03048643']

Types de publication

Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1226-1229

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR001998
Pays : United States

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Références

Prev Med. 2019 Nov;128:105760
pubmed: 31251946
J Nerv Ment Dis. 2003 Mar;191(3):145-53
pubmed: 12637840
Open Forum Infect Dis. 2018 Aug 07;5(9):ofy194
pubmed: 30211247
MMWR Morb Mortal Wkly Rep. 2017 Jun 09;66(22):569-573
pubmed: 28594786
J Subst Abuse Treat. 2018 Sep;92:64-69
pubmed: 30032946
Clin Infect Dis. 2000 Apr;30(4):633-8
pubmed: 10770721
N Engl J Med. 2019 Jan 31;380(5):415-424
pubmed: 30152252
N Engl J Med. 2019 Jan 31;380(5):425-436
pubmed: 30699315
Clin Infect Dis. 2019 Mar 5;68(6):1041-1043
pubmed: 30165395
MMWR Morb Mortal Wkly Rep. 2018 Jun 08;67(22):625-628
pubmed: 29879096
Clin Infect Dis. 2019 Jan 1;68(1):e1-e35
pubmed: 30423035
J Subst Abuse Treat. 1992;9(3):199-213
pubmed: 1334156

Auteurs

Laura C Fanucchi (LC)

Division of Infectious Disease, Center on Drug and Alcohol Research, University of Kentucky, Lexington.

Sharon L Walsh (SL)

Center on Drug and Alcohol Research, University of Kentucky, Lexington.

Alice C Thornton (AC)

Division of Infectious Disease, University of Kentucky, Lexington.

Paul A Nuzzo (PA)

Center on Drug and Alcohol Research, University of Kentucky, Lexington.

Michelle R Lofwall (MR)

Center on Drug and Alcohol Research, University of Kentucky, Lexington.

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Classifications MeSH