Mammary mesenchymal and fibroepithelial lesions: An illustrated cytomorphologic update with differential diagnoses.


Journal

Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 06 05 2019
revised: 08 07 2019
accepted: 15 07 2019
pubmed: 26 7 2019
medline: 21 1 2020
entrez: 26 7 2019
Statut: ppublish

Résumé

The Uniform Approach to Breast Fine Needle Aspiration Biopsy was put forward by a learned group of breast physicians in 1997. This landmark manuscript focused predominantly on diagnosis and reporting of mammary epithelial lesions. Today, most American practitioners turn initially to core biopsy rather than aspiration biopsy for the first line diagnosis of solid breast lesions; however, recent efforts from the International Academy of Cytology have produced a system called the Standardized Reporting of Breast Fine Needle Aspiration Biopsy Cytology (colloquially labeled in 2017 as the "Yokohama System"), suggesting a new interest in breast fine needle aspiration (FNA), especially in resource limited settings or clinical practice settings with experienced breast cytopathologists. Fibroepithelial lesions of the breast comprise a heterogeneous group of biphasic tumors with epithelial and stromal elements. Mesenchymal lesions of the breast include a variety of neoplasms of fibroblastic, myofibroblastic, endothelial, neural, adipocytic, muscular, and osteo-cartilaginous derivations. The cytology of mesenchymal breast lesions is infrequently described in the literature and is mainly limited to case reports and small series. This illustrated review highlights the cytologic features of fibroepithelial and mesenchymal mammary proliferations and discusses differential diagnoses and histomorphologic correlates.

Identifiants

pubmed: 31343114
doi: 10.1002/dc.24288
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1100-1118

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Références

Cibas ES, Ducatman BS. Cytology Diagnostic Principles and Clinical Correlates. 4th ed. Philadelphia: Elsevier; 2014:233-266.
Wang M, He X, Chang Y, Sun G, Thabane L. A sensitivity and specificity comparison of fine needle aspiration cytology and core needle biopsy in evaluation of suspicious breast lesions: a systematic review and metaanalysis. Breast. 2017;31:157-166.
Bardales RH, Stanley MW. Benign spindle and inflammatory lesions of the breast: diagnosis by fine needle aspiration. Diagn Cytopathol. 1995;12:126-130.
Stanley MW, Tani EM, Horwits CA, et al. Primary spindle cell sarcomas of the breast: diagnosis by fine needle aspiration. Diagn Cytopathol. 1988;4:244-249.
Silverman JF, Geisinger KR, Frable WJ. Fine needle aspiration cytology of mesenchymal tumors of the breast. Diagn Cyto. 1988;4:50-58.
Chhieng DC, Cangiarella JF, Waisman J, Fernandez G, Cohen JM. Fine needle aspiration cytology of spindle cell lesions of the breast. Cancer. 1999;87:359-371.
Lakhani SR, Ellis IO, Schnitt SJ, et al. WHO Classification of Tumors of the Breast. 4th ed. Lyon, France: IARC Press; 2012:119-147.
Brogi E. Fibroepithelial neoplasms. In: Hoda S, Brogi E, Koerner FC, Rosen PR, eds. Rosen's Breast Pathology. 4th ed. Philadelphia: Wolters Kluwer; 2014:213-270.
DeMay RM. The Art and Science of Cytopathology. Vol 2. 2th ed. Chicago: ASCP Press; 2012:1052-1118.
Pike AM, Oberman HA. Juvenile (cellular) adenofibromas: a clinicopathologic study. Am J Surg Pathol. 1985;9:730-736.
Song BS, Kim EK, Seol H, et al. Giant juvenile fibroadenoma of the breast: a case report and brief literature review. Ann Pediatr Endocrinol Metab. 2014;19:45-48.
Schnitt SJ, Collins LC. Biopsy Interpretation of the Breast. 3th ed. Philadelphia: Lippincott, Williams and Wilkins; 2017:180-462.
Abe H, Hanasawa K, Naitoh H, Endo Y, Tani T, Kushima R. Invasive ductal carcinoma within a fibroadenoma of the breast. Int J Clin Oncol. 2004;9:334-338.
Kurosumi M, Itokazu R, Mamiy Y, et al. Invasive ductal carcinoma with a predominant intraductal component arising in a fibroadenoma of the breast. Pathol Int. 1994;44:874-877.
Dejmek A, Lindholm K, et al. Frequency of cytologic features in fine needle aspirates from histologically and cytologically diagnosed fibroadenomas. Acta Cytol. 1991;35:695-699.
Lopez-Ferrer P, Jimenez-Heffernan JA, Vicandi B, et al. Fine needle aspiration cytology of breast fibroadenoma. A cytohistologic correlation study of 405 cases. Acta Cytol. 1998;43:579-586.
Yu GH, Sethi S, Cajulis RS, Gokaslan ST, Frias-Hidvegi D. Benign pairs. A useful discriminating feature in fine needle aspirates of the breast. Acta Cytol. 1997;41:721-726.
Sturgis CD, Sethi S, Cajulis RS, Hidvegi DF, Yu GH. Diagnostic significance of benign pairs and signet ring cells in fine needle aspirates of the breast. Cytopathology. 1998;9:308-319.
Tsuchiya S, Maruyama Y, Koike Y, Yamada K, Kobayashi Y, Kagaya A. Cytologic characteristics and origin of naked nuclei in breast aspirate smears. Acta Cytol. 1987;31:285-290.
Malberger E, Yerushalmi R, Tamir A, Keren R. Diagnosis of fibroadenoma in breast fine needle aspirates devoid of typical stroma. Acta Cytol. 1997;41:1483-1488.
Simsir A, Waisman J, Cangiarella J. Fibroadenomas with atypia: causes of under and over diagnosis by aspiration biopsy. Diagn Cytopathol. 2001;25:278-284.
Krishnamurthy S, Ashfaq R, Shin HJ, et al. Distinction of phyllodes tumor from fibroadenoma. Cancer Cytopathol. 2000;90:342-349.
Maritz RM, Michelow PM. Cytological criteria to distinguish phyllodes tumor of the breast from fibroadenoma. Acta Cytol. 2017;61:418-424.
Ali A, Yin D, Yao D, et al. Criteria for the diagnosis of fibroepithelial lesions of the breast with liquid based cytology. Acta Cytol. 2004;48:481-486.
Tsang AK, Chan SK, Lam CC, et al. Phyllodes tumors of the breast-differentiating features in core needle biopsy. Histopathology. 2011;59:600-608.
Choi J, Koo JS. Comparative study of histological features between core needle biopsy and surgical excision in phyllodes tumor. Pathol Int. 2012;62:120-126.
Tan PH, Thike AA, Tan WJ, et al. Predicting clinical behavior of breast phyllodes tumor: a nomogram based on histologic criteria and surgical margins. J Clin Pathol. 2012;65:69-76.
Tan BY, ACS G, Apple SK, et al. Phyllodes tumor of the breast a consensus review. Histopathology 2016;2016:68:5-21.
El Hag IA, Aodah A, Kollur SM, et al. Cytological clues in the distinction between phyllodes tumor and fibroadenoma. Cancer Cytopathol. 2010;118:33-40.
Bhattarai S, Kapila K, Verma K. Phyllodes tumor of the breast. A cytohistologic study of 80 cases. Acta Cytol. 2000;44:790-796.
Jayaram G, Sthaneshwar P. Fine needle aspiration cytology of phyllodes tumors. Diagn Cytopathol. 2002;26:222-227.
Herbert M, Schvimer M, Zehavi S, et al. Breast hamartoma: fine needle aspiration cytologic finding. Cancer. 2003;99:255-258.
Gomez-Aracil V, Mayayo E, Azua J, Mayayo R, Azua-Romeo J, Arraiza A. Fine needle aspiration cytology of mammary hamartoma: a review of nine cases with histologic correlation. Cytopathology. 2003;14:195-200.
Herbert M, Mendlovic S, Liokumovich P, et al. Can hamartoma of the breast be distinguished from fibroadenoma using FNA cytology? Diagn Cytopathol. 2006;34:326-329.
Erickson-Johnson MR, Chou MM, Evers BR, et al. Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. Lab Invest. 2011;91:1427-1433.
Kang A, Kumar JB, Thomas A, et al. A spontaneously resolving breast lesion: imaging and cytological findings of nodular fasciitis of the breast with FISH showing USP6 gene rearrangement. BMJ Case Rep. 2015;213076:1-4.
Tay TKW, Tan PH. Spindle cell lesions of the breast an approach to diagnosis. Seminars in Diagn Pathol. 2017;34:400-409.
Paliogiannis P, Cossu A, Palmier G, et al. Breast nodular fasciitis a comprehensive review. Breast Care. 2016;11:270-274.
Sakuma T, Matsuo K, Koike S, et al. Fine needle aspiration cytology of nodular fasciitis of the breast. Diagn Cytopathol. 2014;43:222-229.
Paker I, Kokenek TD, Kacar A, Ceyhan K, Alper M. Fine needle aspiration cytology of nodular fasciitis presenting as a mass in the male breast: report of an unusual case. Cytopathology. 2013;24:201-203.
Nguyen GK, Shnitka TK, Jewell LD. Aspiration biopsy cytology of mammary myoepithelioma. Diagn Cytopathol. 1987;3:335-338.
Stoll LM, Li QK. Cytology of fine-needle aspiration of inflammatory myofibroblastic tumor. Diagn Cytopathol. 2011;39:663-672.
Neuman HB, Brogi E, Ebrahim A, Brennan MF, van Zee KJ. Desmoid tumors (fibromatoses) of the breast: a 25 year experience. Ann Surg Oncol. 2008;15:274-280.
Krings G, McIntire P, Shin SJ. Myofibroblastic, fibroblastic and myoid lesions of the breast. Semin Diagn Pathol. 2017;34:427-437.
Chhieng DC, Cohen JM. Fine needle aspiration (FNA) cytology of mammary fibromatosis: a case report and review of literature. Cytopathology. 1999;10:354-359.
Lopez-Ferrer P, Jimenez-Heffernan JA, Vicandi B, et al. Fine needle aspiration cytology of mammary fibromatosis: report of two cases. Diagn Cytopathol. 1997;17:363-368.
Chinoy RF, Beotra A, Naresh KN. Fibromatosis of the breast: diagnosis by fine needle aspiration cytology. Acta Cytol. 1998;42:811-812.
Fugen A, Elif S, Gulistan G, et al. Fine needle aspiration cytology of a mammary myofibroblastoma a case report on the role of immunohistochemistry and cell block preparations and a review of the literature. Diagn Cytopathol. 2016;44:1064-1069.
Haj M, Weiss M, Loberant N, Cohen I. Inflammatory pseudotumor of the breast: case report and literature review. Breast J. 2003;9:423-425.
Markopoulos C, Charalampoudis P, Karagiannis E, et al. Inflammatory myofibroblastic tumor of the breast. Case Rep Surg. 2015;705127:1-5.
Akbulut M, Gunhan-Bilgen I, Zekioglu O, Duygulu G, Oktay A, Ozdemir N. Fine needle aspiration cytology of inflammatory myofibroblastic tumor (inflammatory pseudotumor) of the breast: a case report and review of the literature. Cytopathology. 2007;18:384-387.
Alizadeh L, Alkhasawneh A, Reith JD, al-Quran SZ. Epithelioid myofibroblastoma of the breast: a report of two cases with discussion of diagnostic pitfalls. Breast J. 2015;21:669-673.
Odashiro AN, Odashiro Miiji LN, Odashiro DN, Nguyen GK. Mammary Myofibroblastoma: report of two cases with fine-needle aspiration cytology and review of the cytology literature. Diagn Cytopathol. 2004;30:406-410.
Alvarez-Rodriguez F, Gimeno-Aranguez M, Lopez-Varela C, et al. Fine-needle aspiration cytology of mammary myofibroblastoma: a report of six cases. Acta Cytol. 2012;56:501-505.
Sng KK, Tan SM, Mancer JF, et al. The contrasting presentation and management of pseudoangiomatous stromal hyperplasia of the breast. Singapore Med J. 2008;49:82-85.
Lee JW, Jung GS, Kim JB, et al. Pseudoangiomatous stromal hyperplasia presenting as rapidly growing bilateral breast enlargement refractory to surgical excision. Arch Plast Surg. 2016;43:218-221.
Virk RK, Khan A. Pseudoangiomatous stromal hyperplasia: an overview. Arch Pathol Lab Med. 2010;134:1070-1074.
Ferreira M, Albarracin CT, Resetkova E. Pseudoangiomatous stromal hyperplasia tumor: a clinical, radiologic and pathologic study of 26 cases. Mod Pathol. 2008;21:201-2017.
Vicandi B, Jimenez-Heffernan JA, Lopez-Ferrer P, et al. Nodular pseudoangiomatous stromal hyperplasia of breast: cytologic features. Acta Cytol. 1998;42:335-341.
McCluggage WG, Allen M, Anderson NH. Fine needle aspiration cytology of mammary pseudoangiomatous stromal hyperplasia: a case report. Acta Cytol. 1999;43:1147-1149.
Spitz DJ, Reddy VB, Gattuso P. Fine-needle aspiration of pseudoangiomatous stromal hyperplasia of the breast. Diagn Cytopathol. 1999;20:323-324.
Lui PC, Law BK, Chu WC, et al. Fine-needle aspiration cytology of pseudoangiomatous stromal hyperplasia of the breast. Diagn Cytopathol. 2004;30:353-355.
Levine PH, Nimeh D, Guth AA, Cangiarella JF. Aspiration biopsy of nodular pseudoangiomatous stromal hyperplasia of the breast: clinicopathologic correlates in 10 cases. Diagn Cytopathol. 2005;32:345-350.
Ng WK, Chiu CS, Han KC, Chow JC. Mammary pseudoangiomatous stromal hyperplasia: a reappraisal of the fine needle aspiration cytology findings. Acta Cytol. 2003;47:373-380.
Das Gupta TK, Brasfield RD, Strong EW, et al. Benign solitary schwannomas (neurilemomas). Cancer. 1969;24:355-366.
Charu V, Cimino-Mathews A. Peripheral nerve sheath tumors of the breast. Semin Diagn Pathol. 2017;34:420-426.
Gupta RK, Naran S, Lallu S, Fauck R. Fine needle aspiration cytology in neurilemoma (schwannoma) of the breast: report of two cases in a man and a woman. Diagn Cytopathol. 2001;24:76-77.
Bernardello F, Caneva A, Bresaola E, et al. Breast solitary schwannoma: fine needle aspiration biopsy and immunohistochemical analysis. Diagn Cytopathol. 1994;10:221-223.
Thejaswini M, Padmaja K, Srinivasamurthy V, Rao MS. Solitary intramammary schwannoma mimicking phyllodes tumor: cytological clues in the diagnosis. J Cytol. 2012;29:258-260.
Akahane K, Kato K, Ogiso S, et al. Malignant granular cell tumor of the breast: case report and literature review. Breast Cancer. 2015;22:317-323.
Wang YH, Lee MY. Granular cell tumor in male breast masquerading as atypical apocrine neoplasm: a potential diagnostic pitfall in fine needle aspiration cytology. Diagn Cytopathol. 2016;44:612-615.
McCluggage WG, Sloan S, Kenny BD, et al. Fine needle aspiration cytology (FNAC) of mammary granular cell tumor: a report of three cases. Cytopathology. 1999;10:383-389.
Baker GM, Schnitt SJ. Vascular lesions of the breast. Semin Diagn Pathol. 2017;34:410-419.
Fineberg S, Rosen PP. Cutaneous angiosarcoma and atypical vascular lesions of the skin and breast after radiation therapy for breast carcinoma. Am J Clin Pathol. 1994;102:757-763.
Guo T, Zhang L, Chang NE, Singer S, Maki RG, Antonescu CR. Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions. Genes Chromosomes Cancer. 2011;50:25-33.
Brodie C, Provenzano E. Vascular proliferations of the breast. Histopathology. 2008;52:30-44.
Assalia A, Schein M. Severe haemorrhagic complication following needle or open biopsy of a breast mass: suspect angiosarcoma. Br J Surg. 1992;79:469.
Galindo LM, Shienbaum AJ, Dwyer-Joyce L, Garcia FU. Atypical hemangioma of the breast: a diagnostic pitfall in breast fine-needle aspiration. Diagn Cytopathol. 2001;24:215-218.
Geller RL, Hookim K, Sullivan HC, Stuart LN, Edgar MA, Reid MD. Cytologic features of angiosarcoma: a review of 26 cases diagnosed on FNA. Cancer Cytopathol. 2016;124:659-668.
Gherardi G, Rossi S, Perrone S, Scanni A. Angiosarcoma after breast conserving therapy: fine needle aspiration biopsy, immunohistochemistry and clinicopathologic correlates. Cancer. 2005;105:145-151.
Gupta RK, Naran S, Dowle C, et al. Needle aspiration cytology and immunohistochemistry study in a case of angiosarcoma of the breast. Diagn Cytopathol. 1991;7:363-365.
Silver SA, Tavassoli FA. Primary osteogenic sarcoma of the breast: a clinicopathologic analysis of 50 cases. Am J Surg Pathol. 1998;22:925-933.
Trihia H, Valavanis C, Markidou S, Condylis D, Poulianou E, Arapantoni-Dadioti P. Primary osteogenic sarcoma of the breast: cytomorphologic study of 3 cases with histologic correlation. Acta Cytol. 2007;51:443-450.
Pettinato G, Manivel JC, Petrella G, De Chiara A, Calí A. Primary osteogenic sarcoma and osteogenic metaplastic carcinoma of the breast immunocytochemical identification in fine needle aspirates. Acta Cytol. 1989;33:620-626.
Mertens HH, Langnickel D, Staedtler F. Primary osteogenic sarcoma of the breast. Acta Cytol. 1982;26:512-516.
Li DL, Zhou RJ, Yang WT, et al. Rhabdomyosarcoma of the breast: a clinicopathologic study and review of the literature. Chin Med J (Engl). 2012;125:2618-2622.
Hays DM, Donaldson SS, Shimada H, et al. Primary and metastatic rhabdomyosarcoma in the breast: neoplasms of adolescent females, a report from the intergroup rhabdomyosarcoma study. Med Pediatr Oncol. 1997;29:181-189.
Mondal SK, Mandal PK, Adhikari A, Basak B. Primary pleomorphic rhabdomyosarcoma of breast: report of a rare neoplasm. J Res Med Sci. 2014;19:1200-1202.
Orta LY, Beyda JN, Desman GT. Cutaneous / subcutaneous mesenchymal proliferations of the breast: report of a rare neoplasm. Semin Diagn Pathol. 2017;34:470-478.
Koirala K, Shrestha ML, Chalise PR. Leiomyoma of the breast: a report of rare case. Nepal Med Coll J. 2008;10:207-208.
Shah SD, Gupta A, Roy S, Mukhopadhyay S. Intraparenchymal leiomyoma of the breast: a case report. Indian J Surg. 2013;75:88-89.
Gupta RK. Needle aspiration cytology and immunohistochemical findings in a case of leiomyosarcoma of the breast. Diagn Cytopathol. 2007;35:254-256.
Jun Wei X, Hiotis K, Garcia R, Hummel Levine P. Leiomyosarcoma of the breast: a difficult diagnosis on fine needle aspiration biopsy. Diagn Cytopathol. 2003;29:172-178.
Gupta RK, Kenwright D, Naran S, Lallu S, Fauck R. Fine needle aspiration cytodiagnosis of leiomyosarcoma of the breast: a case report. Acta Cytol. 2000;44:1101-1105.
Jayaram G, Jayalakshmi P, Yip CH, et al. Leiomyosarcoma of the breast: report of a case with fine needle aspiration cytologic, histologic and immunohistochemical features. Acta Cytol. 2005;49:656-660.
Rowe JJ, Cheah AL, Calhoun BC. Lipomatous tumors of the breast: a contemporary review. Semin Diagn Pathol. 2017;34:453-461.
Magro G. Differential diagnosis of benign spindle cell lesions. Surg Pathol Clin. 2018;11:91-121.
Lew WY. Spindle cell lipoma of the breast: a case report and literature review. Diagn Cytopathol. 1993;9:434-437.
Lopez-Rios F, Alberti N, Perez-Barrios A, et al. Aspiration biopsy of pleomorphic lipoma of the breast: a case report. Acta Cytol. 2000;44:255-258.
Pant I, Kaur G, Joshi SC, Khalid IA. Myxoid liposarcoma of the breast in a 25-year-old female as a diagnostic pitfall in fine needle aspiration cytology: report of a rare case. Diagn Cytopathol. 2008;36:674-677.
Abati A, Abele J, Bacus SS, et al. The uniform approach to breast fine needle aspiration biopsy national cancer institute fine needle aspiration of breast workshop subcommittees. Diagn Cytopathol. 1997;16:295-311.
Field AS, Schmitt F, Vielh P. IAC standardized reporting of breast fine needle aspiration biopsy cytology. Acta Cytol. 2017;61:3-6.
Howitt BE, Fletcher CD. Mammary type myofibroblastoma: clinicopathologic characterization in a series of 143 cases. Am J Surg Pathol. 2016;40:361-367.
Corso G, Di Nubila B, Ciccia A, et al. Granular cell tumor of the breast: molecular pathology and clinical management. Breast J. 2018;24:778-782.

Auteurs

Ruba A Khattab (RA)

Department of Pathology, University Hospitals of Case Western Reserve University, Cleveland, Ohio.

J Jordi Rowe (JJ)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Christine N Booth (CN)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Nour Sneige (N)

Department of Pathology, Houston Methodist Hospital, Weill Cornell Medical College, Houston, Texas.

Nancy Fong (N)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Liron Pantanowitz (L)

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Olaronke Oshilaja (O)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Jennifer A Brainard (JA)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Erinn P Downs-Kelly (EP)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Andrea Dawson (A)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Charles D Sturgis (CD)

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH